Alcohol, AIDS, and Liver Disease: Preventable Side-effects of Antiretroviral Therapy (R21)

The summary for the Alcohol, AIDS, and Liver Disease: Preventable Side-effects of Antiretroviral Therapy (R21) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Alcohol, AIDS, and Liver Disease: Preventable Side-effects of Antiretroviral Therapy (R21): -Purpose. This Funding Opportunity Announcement (FOA) by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) is intended to stimulate research on new preventive and therapeutic approaches to alcohol- and antiretroviral drug- induced liver disease in patients with AIDS. Alcohol consumption is widely acknowledged as a co-factor in the sexual transmission, susceptibility to infection, and progression of HIV; however a relationship between alcohol use in the context of antiretroviral therapy and adverse outcomes, notably liver disease progression, is less recognized. Recent research indicates that inflammatory pathways predominate in alcoholic hepatitis whereas adaptive immunity plays a primary role in viral hepatitis, offering multiple targets for novel preventive and therapeutic interventions. This FOA emphasizes the need to explore new targets and encourages the development of novel preventive and therapeutic interventions that protect the liver from alcohol and antiretroviral drug- induced liver injury. A better understanding of liver disease should translate to improved care for HIV-infected patients, many of whom continue to consume alcohol. -Mechanism of Support. This Funding Opportunity Announcement (FOA) will utilize the NIH Exploratory/Developmental Grant (R21) award mechanism and runs in parallel with a FOA of identical scientific scope, RFA-AA-08-013, that solicits applications under the R01 mechanism. -Funds Available and Anticipated Number of Awards. The total amount to be awarded under this FOA and the companion FOA (RFA-AA-08-013) is $2 million. The anticipated number of awards is 6-8. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.

Federal Grant Title:	Alcohol, AIDS, and Liver Disease: Preventable Side-effects of Antiretroviral Therapy (R21)
Federal Agency Name:	National Institutes of Health
Grant Categories:	Health
Type of Opportunity:	Discretionary
Funding Opportunity Number:	RFA-AA-08-014
Type of Funding:	Grant
CFDA Numbers:	93.273
CFDA Descriptions:	Alcohol Research Programs
Current Application Deadline:	No deadline provided
Original Application Deadline:	Mar 19, 2008
Posted Date:	Dec 12, 2007
Creation Date:	Dec 12, 2007
Archive Date:	Apr 19, 2008
Total Program Funding:	$2,000,000
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching:	No

Applicants Eligible for this Grant: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments State governments Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Independent school districts City or township governments Small businesses Special district governments Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility: Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply.
Link to Full Grant Announcement: Information not provided
Grant Announcement Contact: NIH OER Webmaster
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