Ancillary Studies to Obesity-Related Clinical Trials

The summary for the Ancillary Studies to Obesity-Related Clinical Trials grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Ancillary Studies to Obesity-Related Clinical Trials: The goal of this initiative is to solicit research grant applications for ancillary studies investigating obesity-related research questions in conjunction with six NIDDK-sponsored cooperative agreement clinical trials and consortia and one NIA-sponsored cooperative agreement. These ancillary study proposals may utilize patients and/or patient materials from the seven clinical cooperative agreements cited below, subject to study- specific restrictions. Acceptable studies will vary depending upon the parent cooperative agreement and may include investigation of the genetic and environmental factors underlying obesity, of the pathogenesis of obesity and associated co-morbidities, of surrogate markers or biomarkers for obesity- related disease and therapeutic effects of interventions, and of new technologies for measurement of diet, physical activity and energy balance. The NIA is particularly interested in ancillary projects elucidating the relationships of aging changes to the above topics. Potential applicants are encouraged to consider any of the cooperative agreements included in this RFA as a resource for addressing aging-relevant research questions. The NCCAM is interested in supporting investigations of complementary or alternative approaches to weight maintenance and the prevention and treatment of overweight or obesity. The following seven major cooperative agreement clinical trials or networks qualify for submission of ancillary studies under this announcement: o Look AHEAD: Action for Health in Diabetes o Diabetes Prevention Program Outcomes Study (DPPOS) o Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) o Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) o Bariatric Surgery Clinical Research Consortium (BSCRC). o Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy (CALERIE) Studies o Weight Reduction for Incontinence Network (WIN) These cooperative agreements are the only trials or networks for which ancillary study applications will be accepted under this announcement. The first two of these cooperative agreements are currently in progress and can accommodate applications for all receipt dates. The NASH CRN, the TODAY study, the Bariatric Surgery Clinical Research Consortium, and the WIN study are still in the design phase and CALERIE is in the pilot testing phase. These five studies will not be ready to accept ancillary study proposals until the later receipt dates.