Approaches to Assessing Potential Food Allergy from Genetically Engineered Plants
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Approaches to Assessing Potential Food Allergy from Genetically Engineered Plants: The U.S. Environmental Protection Agency (EPA), as part of its Science to Achieve Results (STAR) program, is issuing this request for applications (RFA) for applied research on innovative or improved methods to predict whether or not a pesticide protein is a food allergen. Research to characterize the key factors that influence human immune responses to dietary proteins is needed in order to better assess potential food allergy from genetically engineered plants. Proposals are requested on the role of dose, route of sensitization, and/or the physicochemical properties of ingested proteins and their influence on the development of immune sensitization, oral tolerance, or the elicitation of allergic symptoms. Also of interest is how the food matrix and gastrointestinal environment in which proteins are ingested may affect these immune responses. The overall aim of the research program is to improve safety assessment for genetically engineered plants by enhancing the ability to estimate the potency of unknown proteins relative to known allergenic and non-allergenic proteins. Because there is no single, definitive test for determining the allergenic potential of novel pesticide proteins in the diet, risk assessment associated with the regulation of foods derived from modern biotechnology currently uses a "weight-of-evidence" approach. The research will contribute to improved methods for assessing the potential dietary allergenicity of pesticide proteins in genetically engineered plants.
Federal Grant Title: | Approaches to Assessing Potential Food Allergy from Genetically Engineered Plants |
Federal Agency Name: | Environmental Protection Agency |
Grant Categories: | Environment |
Type of Opportunity: | Discretionary |
Funding Opportunity Number: | EPA-G2009-STAR-H1 |
Type of Funding: | Grant |
CFDA Numbers: | 66.509 |
CFDA Descriptions: | Science To Achieve Results (STAR) Research Program |
Current Application Deadline: | Jan 07, 2010 Pleas |
Original Application Deadline: | Jan 07, 2010 Pleas |
Posted Date: | Oct 06, 2009 |
Creation Date: | Oct 06, 2009 |
Archive Date: | Feb 06, 2010 |
Total Program Funding: | $1,700,000 |
Maximum Federal Grant Award: | $425,000 |
Minimum Federal Grant Award: | |
Expected Number of Awards: | 4 |
Cost Sharing or Matching: | No |
- Applicants Eligible for this Grant
- State governments - County governments - City or township governments - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education - Private institutions of higher education - Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Additional Information on Eligibility
- See Section III of the announcement for additional eligibility information.
- Link to Full Grant Announcement
- Information not provided
- Grant Announcement Contact
- Susan Laessig, 202-343-9617.
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