The summary for the Basic Research in Interstitial Cystitis grant is detailed below.
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Basic Research in Interstitial Cystitis: In the present Request for Applications (RFA), the Division of Kidney, Urologic, and Hematologic Diseases (DKUHD) of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) invites applications for basic cellular, molecular, and genetic research and translational studies focused on understanding the causes and pathogenesis of interstitial cystitis (IC). One aim of this RFA is to attract new and established investigators from related research areas to apply their knowledge to the study of IC. Such related areas include: inflammation, epithelial biology, cellular biology, molecular genetics, neuropathology and neurophysiology, the biology and physiology of pain, diagnostic radiology and nuclear medicine, genomics, proteomics, the development of genetic animal models, autoimmunity, etc.. The development of productive research collaborations between investigators with diverse scientific backgrounds is another highly relevant aim of the RFA. This RFA is a part of NIDDK's commitment to encouraging and supporting new and innovative high-quality basic and translational studies that will provide insights into this chronic, painful and disabling disorder.
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