Beta Cell Biology Consortium (U01)

The summary for the Beta Cell Biology Consortium (U01) Federal Grant is detailed below. It contains information such as the Catalog of Federal Domestic Assistance (CFDA) number, who is eligible for the grant, how much grant money will be awarded, important deadlines, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed in the Grant Announcement Contact section. If these sections are incomplete, please visit the website of the government agency that is offering this grant.


	Federal Grant Title:	Beta Cell Biology Consortium (U01)
	CFDA Number:	93.847
	CFDA Description:	Diabetes, Endocrinology and Metabolism Research
	Federal Agency Name:	National Institutes of Health
	Category of Funding Activity:	Food and Nutrition Health
	Category Explanation:	Information not provided
	Opportunity Category:	Discretionary
	Funding Opportunity Number:	RFA-DK-09-011
	Document Type:	Grants Notice
	Funding Instrument Type:	Cooperative Agreement
	Posted Date:	Aug 14, 2009
	Creation Date:	Aug 14, 2009
	Original Closing Date for Applications:	Nov 23, 2009
	Current Closing Date for Applications:	Nov 23, 2009
	Archive Date:	Dec 24, 2009
	Expected Number of Awards:	Information not provided
	Estimated Total Program Funding:	$12,000,000
	Federal Grant Award Ceiling:	Information not provided
	Federal Grant Award Floor:	Information not provided
	Cost Sharing or Matching Requirement:	No

Applicants Eligible for this Grant: State governments - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Native American tribal organizations (other than Federally recognized tribal governments) - Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Non-domestic (non-U.S.) Entities (Foreign Organizations); Tribally Controlled Colleges and Universities (TCCUs) .
Grant Description: Purpose. The National Institute of Diabetes and Digestive and Kidney Diseases invite new U01 applications to participate in a consortium of investigators, the Beta Cell Biology Consortium (BCBC); www.betacell.org . The BCBC will work collaboratively to facilitate research in the following areas: 1) use cues from pancreatic development to directly differentiate pancreatic beta cells and islets from stem/progenitor cells for use in cell-replacement therapies for diabetes; 2) determine how to stimulate beta cell regeneration in the adult pancreas as a basis for improving beta cell mass in diabetic patients; 3) determine how to reprogram progenitor/adult cells into pancreatic beta-cells both in-vitro and in-vivo as a mean for developing cell-replacement therapies for diabetes; and 4) investigate the progression of human type-1 diabetes using patient-derived cells and tissues transplanted in humanized mouse models. The BCBC will be responsible for collaboratively generating the necessary reagents, mouse strains, antibodies, assays, protocols, technologies and validation assays that are beyond the scope of any single research effort proposed by the investigators. Mechanism of Support. This FOA will utilize the U01 grant mechanism. Funds Available and Anticipated Number of Awards. The total amount of funding that the NIDDK expects to award through this announcement in FY2010 is $12 million. The anticipated number of awards is 6-10. Although the financial plans of the NIDDK provide support for the first two years of this program, awards pursuant to this FOA, particularly in years 3 to 5 of the awards, are contingent upon the availability of funds.
Link to Full Grant Announcement: http://grants.nih.gov/grants/guide/rfa-files/rfa-dk-09-011.html
Grant Announcement Contact: NIH OER WebmasterFBOWebmaster@OD.NIH.GOV
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Similar Government Grants: • Pediatric Centers of Excellence in Nephrology (P50); • Nutrition Obesity Research Centers (P30); • George M. OBrien Kidney Research Core Centers (P30); • Cooperative Study Group for Autoimmune Disease Prevention (U01); • Collaborative Interdisciplinary Team Science in NIDDK Research Areas (R24); • PROTEOMIC AND METABOLOMIC APPROACHES TO DIAGNOSE DIABETES AND PRE-DIABETES; • MOLECULAR THERAPY CORE CENTERS; • PILOT AND FEASIBILITY PROGRAM IN HUMAN ISLET BIOLOGY; • DIABETES ENDOCRINOLOGY RESEARCH CENTERS; • CYSTIC FIBROSIS RESEARCH AND TRANSLATION CORE CENTERS