Biology of Breast Pre-Malignancies (R01)

The summary for the Biology of Breast Pre-Malignancies (R01) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Biology of Breast Pre-Malignancies (R01): -Purpose. This Funding Opportunity Announcement (FOA) issued by the National Cancer Institute (NCI) is designed to stimulate multidisciplinary efforts focused on the characterization of the genetic, molecular, and/or cellular changes, and/or functional biology of pre-malignancy states of human breast cancer. The NCI solicits applications for research projects intended to facilitate the identification of those attributes of the earliest identifiable breast lesions that distinguish benign lesions from precancerous lesions. Applicants are encouraged to exploit resources and technologies that already exist, such as: well characterized risk estimates from epidemiologic studies; collections of human specimens and their related clinical and population data; molecular, genetic, and functional tissue characteristics; and analytical, biochemical, genomic, imaging, and nanotechnologies. Projects taking advantage of information already available from well-validated animal model systems and quantitative modeling may also be appropriate. The outcomes of this initiative should enable further basic and translational cancer research with the goal of informing clinical practice. -Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism. -Funds Available and Anticipated Number of Awards. The NCI will award a total of $4.5 million over 3 years to fund two to three individual multidisciplinary research programs. Support for this FOA comes from the Stamp-Out Act, under which the U.S. Postal Service sells a special-issue postage stamps with a surcharge to support breast cancer research.