Computational Toxicology Centers: Development Of Predictive Environmental And Biomedical Computer-Based Simulations And Models

The summary for the Computational Toxicology Centers: Development Of Predictive Environmental And Biomedical Computer-Based Simulations And Models grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the Environmental Protection Agency, which is the U.S. government agency offering this grant.

Computational Toxicology Centers: Development Of Predictive Environmental And Biomedical Computer-Based Simulations And Models: The U.S. Environmental Protection Agency (EPA), as part of its Science to Achieve Results (STAR) program, is seeking applications proposing to develop in silico modeling applications of biological systems in areas as diverse as receptor-ligand interactions in cell signaling, simulated organ dysfunction (e.g., heart, liver, kidney), and systemic response to environmental toxicants and pollutants. The STAR program is issuing this request for applications (RFA) for research that will seek to apply high-performance computing technologies and theoretical mathematical techniques to facilitate the development of a predictive capacity for estimating outcomes or risk associated with particular toxicity processes as a result of environmental exposure to pollutants and toxicants. The development of predictive computational modeling of whole biological systems from cells to organs has the potential to address environmental and human health factors with broad scientific and environmental or economic impacts. The overall goal of the computational research effort supported by the U.S. EPA is to develop the use of computational approaches to provide tools for quantitative risk assessment and more efficient strategies for prioritizing chemicals for screening and testing. Through the support of the computational toxicology initiative, EPA will fund research that addresses data gaps in environmental and human health risk assessment and will strengthen the ability of predictive scientific data to guide sound future scientific policy, decisions, and research. To support the development of predictive mathematical models and simulations, the Computational Toxicology Centers will be funded for up to 4 years. A research Center is operated through a university, non-profit, or governmental entity to conduct complex, long-term, and collaborative research projects using multi-disciplinary approaches. A research Center is a consortium of investigators who will work together to address the investigational areas being solicited. (see eligibility information section for eligible applicants).