Controlling Cellular Machinery - Diagnostics and Therapeutics

The summary for the Controlling Cellular Machinery - Diagnostics and Therapeutics Federal Grant is detailed below. It contains information such as the Catalog of Federal Domestic Assistance (CFDA) number, who is eligible for the grant, how much grant money will be awarded, important deadlines, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed in the Grant Announcement Contact section. If these sections are incomplete, please visit the website of the government agency that is offering this grant.


Federal Grant Title: Controlling Cellular Machinery - Diagnostics and Therapeutics
CFDA Number: 12.910
CFDA Description: Research and Technology Development
Federal Agency Name: DARPA Defense Sciences Office
Category of Funding Activity: Science and Technology
Category Explanation: Information not provided
Opportunity Category: Discretionary
Funding Opportunity Number: DARPA-BAA-11-23
Document Type: Grants Notice
Funding Instrument Type: Cooperative Agreement Procurement Contract
Posted Date: Nov 29, 2010
Creation Date: Nov 29, 2010
Original Closing Date for Applications: Mar 03, 2011
Current Closing Date for Applications: Mar 03, 2011
Archive Date: May 03, 2011
Expected Number of Awards: Information not provided
Estimated Total Program Funding: Information not provided
Federal Grant Award Ceiling: Information not provided
Federal Grant Award Floor: Information not provided
Cost Sharing or Matching Requirement: No

Applicants Eligible for this Grant
Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Additional Information on Eligibility
Information not provided
Grant Description
DARPA is soliciting research proposals for the development of synthetic regulatory genetic elements that can be used in mammalian cells. The proposed research should comprise approaches that enable fundamental advances to the development and broad application of synthetic regulatory elements for in vivo biomedical applications to detect, treat, or prevent disease. Technical challenges that need to be addressed include, but are not limited to, discovery, characterization, evolution or design, and demonstration of orthogonal and modular genetic regulatory elements; construct stability and function in the cell; and synthesis, amplification, and delivery of novel circuits in mammalian cells. The designed modules must limit specific interactions with the cellular metabolism or milieu to the desired performance characteristics and demonstrate maintenance of independent function without interference long enough to achieve the intended clinical effect. Specifically excluded is research that primarily results in evolutionary improvements to the existing state of practice. Proposers that intend to pursue nucleic acid vaccines as an application are referred to the companion announcement, Controlling Cellular Machinery - Vaccines, DARPA-BAA-11-22.
Link to Full Grant Announcement
Information not provided
Grant Announcement Contact
Dr. Daniel Wattendorf

BAA Coordinator [DARPA-BAA-11-23@darpa.mil]
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