Cooperative Centers for Translational Research on Human Immunology and Biodefense

The summary for the Cooperative Centers for Translational Research on Human Immunology and Biodefense grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Cooperative Centers for Translational Research on Human Immunology and Biodefense: The National Institute of Allergy and Infectious Diseases (NIAID) invites applications from single institutions or consortia of institutions to establish Cooperative Centers for Translational Research on Human Immunology and Biodefense. The long-term goal of this program is the translation of research using animal models of immunity to infection into clinical applications in humans. The immediate purpose is to support stable, flexible, centralized infrastructure and research needed to promote and coordinate multidisciplinary basic and clinical research in human immunology as it relates to defense against agents of bioterrorism and emerging/re-emerging infectious diseases. The program will be milestone-based, and will include the flexibility to quickly redirect or replace research projects during the funding period. Funding beyond the first year will be contingent upon satisfactory progress in meeting negotiated milestones. The Cooperative Agreement mechanism (U19), together with the Exploratory Planning Grant mechanism (R21), will be used to support the development of multi-investigator teams with a scope of activities not possible with other funding mechanisms. Each Center will consist of at least five components: (1) Research Resource Technical Development of assays, reagents, and technologies to advance more rapid and more definitive analyses of human immune responses; (2) a minimum of three Research Projects focused on understanding human immune response and regulation in the context of NIAID Category A-C pathogens or their products (see list at http://www.niaid.nih.gov/dmid/bioterrorism/bandc_priority.htm);note that clinical trials, HIV research, and behavioral research will not be supported by this program; (3) Core Facilities to support the research projects or to facilitate management of the Center; (4) short-term Pilot Projects; and (5) an Education Component focused on short-term training in the technical or theoretical aspects of human immunology research and biodefense. Synergistic interaction is a key feature of this program. Each Center will provide unique and complementary strengths in terms of technical potential and specific areas of immunological investigation, and all Centers will share responsibility for program development and resource coordination via a Centers Steering Committee. Applicants must include research projects that address a central theme of immunological interest in the context of biodefense, as well as describe the unique technical expertise offered for the development and utilization of assays, reagents, and technologies. All applicants must comply with the requirements outlined in the section below entitled "SPECIAL REQUIREMENTS."