Coordination of Vascularization and Lung Development

The summary for the Coordination of Vascularization and Lung Development grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Coordination of Vascularization and Lung Development: The National Heart, Lung, and Blood Institute (NHLBI) invites applications to address the interactive relationships between vasculogenesis, including angiogenic/angiostatic modulation, and the developing lung. The purpose of this RFA is to stimulate research that will increase our knowledge of these interactive processes by supporting fundamental studies focusing on the cellular and molecular mechanisms that coordinate the formation of the lung and its vasculature during the process of normal lung development or that contribute to arrested or aberrant lung development. It is expected that these studies will involve a systems biology approach to lung development and will gather information on the temporo-spatial expression of regulatory genes, growth factors and receptors involved in the process of vasculogenesis and angiogenesis during lung development. Such new information would provide the basis for intervention to reverse arrested alveolization, which is a feature of the chronic lung disease observed in very-low- birth-weight premature infants. Such new information might also clarify some of the apparent associations between early developmental events and the pathobiology of adult lung disease.