Department of Defense (DOD) FY05 Tuberous Sclerosis Complex Research Program (TSCRP) Natural History Development Award (NHDA)

The summary for the Department of Defense (DOD) FY05 Tuberous Sclerosis Complex Research Program (TSCRP) Natural History Development Award (NHDA) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the Dept of the Army USAMRAA, which is the U.S. government agency offering this grant.

Department of Defense (DOD) FY05 Tuberous Sclerosis Complex Research Program (TSCRP) Natural History Development Award (NHDA): The United States Army Medical Research and Materiel Command (USAMRMC), Office of the Congressionally Directed Medical Research Programs (CDMRP) invites applications for funding for the Fiscal year 2005 Tuberous Sclerosis Complex Research Program (TSCRP) Natural History Development Award. The intent of the Natural History Development Award is to support the development of a focused, hypothesis-driven natural history study that will enhance the current knowledge of TSC manifestations and improve clinical management of the disorder and/or the development and clinical testing of new interventions. Recipients of the Natural History Development Award will be required to submit a proposal, clinical protocol, and informed consent/assent form(s) for the Natural History Study Award in FY06, pending receipt of funds by the TSCRP. This mechanism is not intended to support descriptive, broad-based proposals that are limited to collecting information (clinical, pathological, radiographical, or other) with no accompanying analysis or hypothesis testing. Instead, proposals must include a specific hypothesis or question regarding the natural history of TSC; detailed plans to develop a study to test the hypothesis or answer the question; and discussion of how the proposed study will improve clinical management and/or facilitate the development of TSC clinical trials. Proposals should outline plans for the establishment of the research team, the development of tools for data management and trial/research administration, the definition of participant recruitment strategies, and the development of the clinical protocol and other essential components of the study included in a Manual of Operations and Procedures. Approximately $0.15 million (M) is available to fund the FY05 TSCRP Natural History Development Award. Depending on the number and quality of the applications, it is anticipated that one proposal will be funded. Funding for the FY05 Natural History Development Award can be requested for $150,000 for 18 months, inclusive of both direct and indirect costs. FY05 funding will be disbursed in two installments, one installment of $100,000 at the time of the award and the second installment of $50,000 contingent upon submission of a compliant FY06 Natural History Study Award proposal, clinical protocol, and informed consent form. Electronic submission is required. Proposals will be accepted only as PDF files submitted through the CDMRP eReceipt system. No paper copy submissions will be accepted. The CDMRP uses a two-tier review process for proposals: scientific peer review, followed by programmatic review. Details of both tiers of review can be found in the Full Text of Program Announcement. Estimated timelines for the FY05 Natural History Development Award are as follows: Full Proposal Submission Deadline: February 22, 2005, 5:00 p.m. Eastern Time; Peer Review: April, 2005; Programmatic Review: July, 2005; Award Start Date: Between September, 2005 and January, 2006. For additional information or questions, please contact: Patricia A. Evans, Contracting/Grants Office, U.S. Army Medical Research Acquisition Activity, 820 Chandler Street, Fort Detrick, MD 21702-5014, phone: (301) 619-7354, Fax: (301) 619-6662, email: [email protected]