Department of Defense(DoD) Breast Cancer Research Program(BCRP) Center of Excellence (COE)

The summary for the Department of Defense(DoD) Breast Cancer Research Program(BCRP) Center of Excellence (COE) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the Department of Defense, which is the U.S. government agency offering this grant.

Department of Defense(DoD) Breast Cancer Research Program(BCRP) Center of Excellence (COE): The overall goal of the FY06 BCRP is to promote research focused on eradicating breast cancer. Therefore, the BCRP challenges the scientific community to design innovative research that will foster new directions for, address neglected issues in, and bring new investigators to the field of breast cancer research. The BCRP focuses its funding on innovative projects, particularly those involving multidisciplinary and/or multi-institutional collaborations and alliances that have the potential to make a significant impact on breast cancer. Projects that address underinvestigated avenues of research or novel applications of existing technologies are strongly encouraged. The BCRP encourages risk-taking research; however, all projects must demonstrate solid scientific judgment and rationale.The BCRPs objective within this context is to fund a balanced portfolio of scientifically meritorious research related to all aspects of breast cancer. The BCRP seeks proposals from all areas of laboratory, clinical, behavioral, and epidemiologic research, including all disciplines within the basic, clinical, psychosocial, behavioral, sociocultural, and environmental sciences, nursing; occupational health, alternative therapies, public health and policy, ethics, and economics. Proposals that address the needs of minority, low-income, rural, and other underrepresented and/or medically underserved populations are strongly encouraged.The Breast Cancer Center of Excellence (COE) Award is designed to accelerate the solution of major overarching questions that will have a significant impact on the prevention, detection, diagnosis, and/or treatment of breast cancer. A synergistic, highly integrated, multidisciplinary research team must be assembled into an integrated consortium to address a central problem in a way that could not be accomplished by a single investigator or group. Unless an exceptionally compelling case is made that a single institution can best address the aims of the COE Award, proposed COEs must be multi-institutional, synergistic, highly integrated, multidisciplinary teams of the best scientists, clinicians, and consumer advocates. The central problem addressed by each COE should (1) solve a major problem(s) in basic, translational, population-based, and/or clinical breast cancer research; (2) develop critically needed resources and/or (3) create a unique new approach to a critical problem in breast cancer research or patient care. These awards may include Phase I or Phase II clinical trials and collaborations with pharmaceutical or biotechnology industry scientists and/or companies, as appropriate. All investigators interested in applying for a COE Award must submit a preproposal. Full proposals will be submitted based upon invitation. Do not submit a full COE Award proposal unless you receive a letter of invitation. The CDMRP expects to allot approximately $24 M of the $127.5M FY06 BCRP appropriation to fund approximately 1 or 2 Breast Cancer COE Awards, depending on the quality and number of proposals received. Funding for COE Awards can be requested for a maximum of $10M in direct costs over the performance period. The performance period can be requested for up to 5 years. Indirect costs should be added as appropriate. Proposals requesting lower levels of funding may also be submitted. No more than $5M will be granted in any single year during the lifetime of the award.Funding will be disbursed in installments. The first installment will be made at the time of the award; subsequent installments will be contingent upon the successful completion of specific milestones. Milestones from the approved Statement of Work will be determined during the award negotiation process. Failure to complete each milestone may result in forfeiture of the subsequent installment of Breast Cancer COE Award funding. The nature of the BCRP does not allow for renewal of grants or supplementation of existing grants. Estimated timelines for the FY06 BCRP Center of Excellence Award are as follows: PreProposals are due by, April 11, 2006 5:00 p.m. Eastern time and Proposal Submission is due July 25, 2006, 5:00 p.m. Eastern time. Electronic submission is required. Proposal will be accepted only as PDF files submitted through the CDMRP eReceipt system. The CDMRP uses a two tier review process for proposals: scientific peer review, followed by programmatic review. Details of both tiers of review can be found in the full text of the Program Announcement. Applicants should submit questions as early as possible. Every effort will be made to answer questions within 5 working days. Phone: 301-619-7079, Fax: 301-619-7792, e-mail : [email protected], Mail: Commander U.S. Army Medical Research and Materiel Command, ATN: MCMR-ZB-C (W871XWH-06-BCRP-COE), 1077 Patchel Street(Building 1077), Fort Detrick, MD 21702-5024.