Development of High Resolution Probes for Cellular Imaging (R01)

The summary for the Development of High Resolution Probes for Cellular Imaging (R01) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Development of High Resolution Probes for Cellular Imaging (R01): -Purpose. The National Institute of General Medical Sciences (NIGMS) and the National Human Genome Research Institute (NHGRI) invite applications to support multi-investigator teams to develop new technologies to enable high sensitivity molecular detection in living cells. The purpose of this funding opportunity is to encourage and facilitate novel, high-risk strategies to create fundamentally new probes with enhanced spectral characteristics with the goal of improving detection schemes by a factor of 10 to 100. Parallel improvements in probe targeting, cellular delivery, and signal detection are also encouraged. The ultimate goal will be to develop probes and delivery strategies that can be used routinely to achieve single molecule sensitivity for imaging dynamic processes within living cells. -Mechanism of Support. . This funding opportunity will utilize the NIH Research Project Grant (R01) award mechanism -Funds Available and Anticipated Number of Awards. The participating Institutes intend to commit approximately $5 million in FY 2008 to fund 6 to 8 multi-investigator R01 grants, each with a budget for total direct costs of up to $500,000 per year, in response to this funding opportunity. Awards issued under this funding opportunity are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received.