Diagnostic and Pharmacokinetic Research in Pediatric HIV/TB and Effects of Co-infection on the Central Nervous System (R01)

The summary for the Diagnostic and Pharmacokinetic Research in Pediatric HIV/TB and Effects of Co-infection on the Central Nervous System (R01) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Diagnostic and Pharmacokinetic Research in Pediatric HIV/TB and Effects of Co-infection on the Central Nervous System (R01): -Purpose. This Funding Opportunity Announcement (FOA), issued by the National Institute of Child Health and Human Development (NICHD) and the National Institute of Mental Health NIMH), solicits Research Project Grant (R01) applications from institutions/organizations that propose improved modalities for the diagnosis of tuberculosis (TB) infection and disease, including MDR and XDR TB, in children with HIV/TB co-infection. Applications are also invited for the evaluation of the pharmacokinetics of first- and second-line anti-tubercular medications, as well as pharmacokinetic drug interactions between these and antiretroviral medications in children with HIV/TB co-infection. Finally, applications are solicited for research to evaluate the effect of HIV/TB co-infection in children on the central nervous system. This FOA is intended to stimulate research to improve the diagnosis and treatment of HIV-infected children with tuberculosis (TB) co-infection, and to form a basis for future research and clinical care. -Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism. -Funds Available and Anticipated Number of Awards. The NICHD intends to commit $1.4 million, and NIMH intends to commit $500,000 in FY 2008 to support three to six meritorious applications. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.