Eradication of Invasive Quagga and Zebra Mussels Using Engineered Disseminated Neoplasia
The summary for the Eradication of Invasive Quagga and Zebra Mussels Using Engineered Disseminated Neoplasia grant is detailed below.
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Eradication of Invasive Quagga and Zebra Mussels Using Engineered Disseminated Neoplasia: Under this Agreement, Biomilab, LLC. shall work to engineer normal quagga and zebra mussel hemocytes into “induced” DN cells (iDNCs) that can be used to transmit and foster lethal cancer into populations of these invasive species in open waters. Major tasks for the project include, but are not limited to: • Establish a facility for the maintenance of live zebra and quagga mussels • Determine methods and conditions for extended culture of explanted and dissociated mussel cells, and establish methods for their genetic modification • Determine methods for the transplantation/engraftment and survival of cultured cells to live mussels and complete characterization of target genes and gene products for use in genomic modification • Convert dreissenid mussel hemocytes to genetically-modified hemic disseminated neoplasia cells (iDNCs) and establishment of methods for long-term culture, expansion, and cryopreservation of iDNCs • Introduction of iDNCs to live quagga/zebra mussels and control mussels, and analysis of engraftment, dissemination, and toxicity
Federal Grant Title: | Eradication of Invasive Quagga and Zebra Mussels Using Engineered Disseminated Neoplasia |
Federal Agency Name: | Bureau of Reclamation (DOI-BOR) |
Grant Categories: | Science and Technology |
Type of Opportunity: | Discretionary |
Funding Opportunity Number: | BOR-DO-19-N020 |
Type of Funding: | Cooperative Agreement |
CFDA Numbers: | 15.560 |
CFDA Descriptions: | Information not provided |
Current Application Deadline: | June 27th, 2019 |
Original Application Deadline: | June 27th, 2019 |
Posted Date: | June 18th, 2019 |
Creation Date: | June 18th, 2019 |
Archive Date: | June 28th, 2019 |
Total Program Funding: | |
Maximum Federal Grant Award: | $1,500,000 |
Minimum Federal Grant Award: | $1 |
Expected Number of Awards: | 1 |
Cost Sharing or Matching: | No |
Last Updated: | June 18th, 2019 |
- Applicants Eligible for this Grant
- Others (see text field entitled "Additional Information on Eligibility" for clarification.)
- Additional Information on Eligibility
- Biomilab, Inc.
- Grant Announcement Contact
- Irene M Hoiby
Supervisory Grants Management Specialist
Phone 303-445-2025
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