Genomic Research in AAT-Deficiency and Sarcoidosis study (GRADS) Cooperative Research Project Grant: Clinical Centers (U01)

The summary for the Genomic Research in AAT-Deficiency and Sarcoidosis study (GRADS) Cooperative Research Project Grant: Clinical Centers (U01) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.
Genomic Research in AAT-Deficiency and Sarcoidosis study (GRADS) Cooperative Research Project Grant: Clinical Centers (U01): The purpose of this funding opportunity announcement (FOA), issued by NHLBI, NIH, is to invite applications to participate in the NHLBI Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis (GRADS) program, which will assemble a multidisciplinary team of investigators to conduct state-of-art genomic, microbiomics and phenotypic studies of two serious and understudied conditions that affect the lungs: Alpha-1 Antitrypsin Deficiency (AAT) and sarcoidosis. GRADS will include up to eight Clinical Centers and one Genomics and Informatics Center (GIC). This FOA solicits applications for Clinical Centers and runs in parallel with a separate FOA that solicits applications for the GIC (see RFA-HL-12-014). The GRADS Clinical Centers will participate in a study-wide protocol by enrolling, clinically and immunologically phenotyping participants, and collecting and processing biospecimens to be shipped to the GIC for genomics and microbiomics analyses. Additionally, each Clinical Center will develop a clinic-specific research protocol aimed at identifying pathogenetic mechanisms or predictors of AAT or sarcoidosis disease development/progression. Collectively the GRADS Clinical Centers will create a program-wide cohort of approximately 400 AAT and approximately 200 sarcoidosis subjects and controls. Up to 8 Clinical Centers will be funded, each led by one or more Investigators with expertise in AAT, sarcoidosis, pulmonary medicine, immunology, genomics or cell biology. A Steering Committee of all the Clinical Center Principal Investigators will be organized by the GIC (see RFA-HL-12-014) to develop the study-wide protocol(s) and monitor study operations.
Federal Grant Title: Genomic Research in AAT-Deficiency and Sarcoidosis study (GRADS) Cooperative Research Project Grant: Clinical Centers (U01)
Federal Agency Name: National Institutes of Health
Grant Categories: Health
Type of Opportunity: Discretionary
Funding Opportunity Number: RFA-HL-12-013
Type of Funding: Cooperative Agreement
CFDA Numbers: 93.838
CFDA Descriptions: Lung Diseases Research
Current Application Deadline: May 17, 2011
Original Application Deadline: May 17, 2011
Posted Date: February 2nd, 2011
Creation Date: Feb 02, 2011
Archive Date: Jun 17, 2011
Total Program Funding: $12,000,000
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching: No
Applicants Eligible for this Grant
State governments - County governments - City or township governments - Special district governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Public housing authorities/Indian housing authorities - Native American tribal organizations (other than Federally recognized tribal governments) - Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Link to Full Grant Announcement
Information not provided
Grant Announcement Contact
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