Metabolomics for a Low Carbon Society

The summary for the Metabolomics for a Low Carbon Society Federal Grant is detailed below. It contains information such as the Catalog of Federal Domestic Assistance (CFDA) number, who is eligible for the grant, how much grant money will be awarded, important deadlines, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed in the Grant Announcement Contact section. If these sections are incomplete, please visit the website of the government agency that is offering this grant.


	Federal Grant Title:	Metabolomics for a Low Carbon Society
	CFDA Number:	47.074
	CFDA Description:	Biological Sciences
	Federal Agency Name:	National Science Foundation
	Category of Funding Activity:	Science and Technology
	Category Explanation:	Information not provided
	Opportunity Category:	Discretionary
	Funding Opportunity Number:	11-527
	Document Type:	Grants Notice
	Funding Instrument Type:	Grant
	Posted Date:	Feb 09, 2011
	Creation Date:	Feb 09, 2011
	Original Closing Date for Applications:	May 13, 2011 Full Proposal Deadline(s): May 13, 2011
	Current Closing Date for Applications:	May 13, 2011 Full Proposal Deadline(s): May 13, 2011
	Archive Date:	Information not provided
	Expected Number of Awards:	4
	Estimated Total Program Funding:	2,000,000
	Federal Grant Award Ceiling:	Information not provided
	Federal Grant Award Floor:	2,000,000
	Cost Sharing or Matching Requirement:	Yes

Applicants Eligible for this Grant: Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility: *Organization Limit: Proposals may only be submitted by the following: - U.S. academic institutions, U.S. non-profit research organizations including museums, research laboratories, professional societies and similar organizations in the U.S. that are directly associated with educational or research activities, and consortia of only the eligible organizations listed here, that have a U.S. campus. When a consortium of eligible organizations submits a proposal, it must be submitted as a single proposal with one organization serving as the lead and all other organizations as subawardees. Separately submitted collaborative proposals will not be accepted and will be returned without review. Organizations ineligible to respond to this program solicitation may not receive subawards. *PI Limit: This solicitation is open only to researchers: (1) located at eligible U.S. institutions; and (2) whose Japanese partners have submitted an identical proposal to the Japan Science and Technology Agency by the announced deadline for the program.
Grant Description: This is a U.S.-Japan joint program coordinated by the National Science Foundation and the Japan Science and Technology Agency (JST). Proposals submitted in response to this solicitation must represent joint projects involving both US and Japanese research groups. JST and NSF will jointly manage the proposal review and award process. The "metabolome" is the complete set of metabolites expressed within an organism. Its composition is a reflection of the networks of enzymatic pathways encoded within the genome as well as the interplay of developmental processes and a changing environment over the lifetime of the organism. Metabolomics has exciting applications in bioenergy, environmental interactions, functional genomics and gene discovery, secondary metabolism, genome-wide association mapping, systems biology and metabolic modeling in plant, algal, and microbial systems. However, the scientific promise of metabolomics currently faces multiple challenges that need to be addressed. These challenges include: how to define the metabolome, metabolite annotation, standardization of spatially and temporally resolved sampling, measurement of metabolite flux, dynamic range and depth-of-coverage, instrumentation and infrastructure, informatics and databases. The goal of this joint NSF-JST program is to advance novel biological knowledge in metabolomics in the areas of energy and the environment, and to foster greater collaborative interactions between Japanese and U.S. scientists in these priority areas. The focus of METABOLOMICS will be on plants, microbes, and algae and eligible research areas will include but will not be limited to: Capture of all major metabolitesDevelopment of standards and annotation of unknown metabolitesIdentification of specialized metabolites of potential value In recent years, metabolomics has matured to the point where it is now possible to consider cataloging the complete profiles of small molecules in cells. Such profiling is critically important because these small molecule metabolites are the end products of gene expression and represent the high-resolution biochemical phenotype of the cell, tissue, and organism. Key goals of metabolomics include 1) chemical annotation, i.e. determining the chemical structure of each molecule, 2) biological annotation, i.e. connecting each metabolite to a specific enzyme, biochemical pathway, or biological process, and 3) metabolomic annotation, i.e. the distribution of each metabolite in different cells of an organism which includes spatial and temporal information as well as concentration.
Link to Full Grant Announcement: http://www.nsf.gov/publications/pub_summ.jsp?ods_key=nsf11527
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