Microbiome of the Lung and Respiratory Tract in HIV-Infected Individuals and HIV-Uninfected Controls (U01)

The summary for the Microbiome of the Lung and Respiratory Tract in HIV-Infected Individuals and HIV-Uninfected Controls (U01) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Microbiome of the Lung and Respiratory Tract in HIV-Infected Individuals and HIV-Uninfected Controls (U01): Purpose.The National Heart, Lung, and Blood Institute (NHLBI) solicits grant applications under this Funding Opportunity Announcement (FOA) to characterize the microbiome of the lung (the airways and airspaces below the glottis and the lung parenchyma) alone or in combination with the nasal and/or oropharyngeal cavities in HIV-infected individuals and matched HIV-uninfected controls, including normal healthy controls, using molecular techniques to identify bacteria and if possible other organisms, e.g., viruses, cell-wall deficient organisms, protozoa, and fungi. Investigators should use high-throughput technology platforms to create a data set of sufficient quality and depth to allow analysis of how changes of microbiota relate to HIV lung disease progression/complications.These data will be used to examine the impact of changes in the respiratory microbiome on the pathogenesis and progression of HIV disease, on HIV-related respiratory complications, and the effects of anti-HIV therapies. The National Heart, Lung, and Blood Institute (NHLBI) invites applications for four Clinical/Sequencing research sites and one supporting Data Coordinating Center (DCC).Each application for a clinical/sequencing research site should propose approaches to characterize the lung microbiome and applicants are encouraged to include at least one hypothesis-driven mechanistic aim.Applicants must agree to collaborate with the other Clinical/Sequencing sites, the DCC, and projects funded under the Roadmap HMP program on overlapping areas of interest.Inclusion of the nasal and or pharyngeal cavities is optional.The Lung HIV Microbiome Program is designed to promote cooperation and coordination, facilitate scientific exchange, and leverage resources.

Federal Grant Title:	Microbiome of the Lung and Respiratory Tract in HIV-Infected Individuals and HIV-Uninfected Controls (U01)
Federal Agency Name:	National Institutes of Health
Grant Categories:	Health
Type of Opportunity:	Discretionary
Funding Opportunity Number:	RFA-HL-09-006
Type of Funding:	Cooperative Agreement
CFDA Numbers:	93.838
CFDA Descriptions:	Lung Diseases Research
Current Application Deadline:	No deadline provided
Original Application Deadline:	Mar 25, 2009
Posted Date:	Oct 31, 2008
Creation Date:	Dec 04, 2008
Archive Date:	Dec 05, 2008
Total Program Funding:	$4,000,000
Maximum Federal Grant Award:	$525,000
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching:	No

Applicants Eligible for this Grant: Special district governments State governments Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Others (see text field entitled "Additional Information on Eligibility" for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities For profit organizations other than small businesses Small businesses Independent school districts City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Link to Full Grant Announcement: Information not provided
Grant Announcement Contact: NIH OER Webmaster
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