New Methodologies for Natural Products Chemistry (R01)

The summary for the New Methodologies for Natural Products Chemistry (R01) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

New Methodologies for Natural Products Chemistry (R01): Purpose. This initiative, a component of the NIH Molecular Libraries (ML) Roadmap program (MLP), will support the development of new methodologies for natural products (NP) chemistry. The long-term goal is to reinvigorate the investigation of nature as a prolific source of bioactive small molecules, with the potential to probe the roles of a wide range of proteins in cellular processes, and/or be developed into new drugs. Samples of NPs that are produced in the course of these studies will be provided to the ML Small Molecule Repository (MLSMR), for use in high-throughput biological screening by the Molecular Libraries Probe Production Centers Network (MLPCN). Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism. Funds Available and Anticipated Number of Awards. The NIH intends to commit up to $2.5 million per year (total costs) to support 6 grants. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the projects that are proposed. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. Ordinarily, the total project period for an application submitted in response to this FOA will be three years. Requests for four years of support will be considered if there is a sufficiently compelling justification, and if funds are available. Ordinarily, a maximum of $250,000 (direct costs) per year may be requested. A larger budget request may be considered, if there is a sufficiently compelling justification, and if funds are available. Eligible Institutions/Organizations. Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Small Business; For-Profit Organization (Other than Small Business); Non-domestic (non-U.S.) Entity (Foreign Organization); Units of State Government; Units of Local Government; Eligible Agencies of the Federal Government Eligible Project Directors/Principal Investigators (PDs/PIs). Individuals with the skills, knowledge, and resources necessary to carry out the proposed research are invited to work with their institution/organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support. Number of Applications. Applicants may submit more than one application, provided each application is scientifically distinct. Renewals and Resubmissions. Both new and competing renewal applications will be accepted under this FOA. Resubmissions (formerly known as Revisions ) of unsuccessful applications originally submitted in response to RFA-RM-05-013 will not be accepted but may be submitted as new applications, with suitable modifications. It is not known at this time whether this FOA will be reissued. Number of PDs/PIs. More than one PD/PI, or multiple PDs/PIs, may be designated on the application.