PILOT AND FEASIBILITY PROGRAM IN HUMAN ISLET BIOLOGY

The summary for the PILOT AND FEASIBILITY PROGRAM IN HUMAN ISLET BIOLOGY Federal Grant is detailed below. It contains information such as the Catalog of Federal Domestic Assistance (CFDA) number, who is eligible for the grant, how much grant money will be awarded, important deadlines, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed in the Grant Announcement Contact section. If these sections are incomplete, please visit the website of the government agency that is offering this grant.


	Federal Grant Title:	PILOT AND FEASIBILITY PROGRAM IN HUMAN ISLET BIOLOGY
	CFDA Number:	93.847
	CFDA Description:	Diabetes, Endocrinology and Metabolism Research
	Federal Agency Name:	National Institutes of Health
	Category of Funding Activity:	Health
	Category Explanation:	Information not provided
	Opportunity Category:	Discretionary
	Funding Opportunity Number:	RFA-DK-03-021
	Document Type:	Grants Notice
	Funding Instrument Type:	Grant
	Posted Date:	Jul 22, 2003
	Creation Date:	Aug 19, 2004
	Original Closing Date for Applications:	November 20, 2003 and July 20, 2004
	Current Closing Date for Applications:	Information not provided
	Archive Date:	Aug 19, 2004
	Expected Number of Awards:	Information not provided
	Estimated Total Program Funding:	Information not provided
	Federal Grant Award Ceiling:	Information not provided
	Federal Grant Award Floor:	Information not provided
	Cost Sharing or Matching Requirement:	No

Applicants Eligible for this Grant: State governments County governments City or township governments Special district governments Independent school districts Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Small businesses Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility: Information not provided
Grant Description: Much of our understanding of the basic biology and function of the beta cell and the pancreatic islet comes from studies of immortalized cell lines and mouse tissue. However, differences in the general structure and organization of mouse and human islets have been identified, and it remains uncertain if these structural differences reflect functional differences as well. With the variable success in islet transplantation and the inability to use in vitro data to reliably predict islet engraftment and function, it is important to learn all that we can about the structure, organization, and signaling properties of human islets, and to compare and contrast these findings with those reported with rodent models of islet function used to date. The information gained from these studies should increase our ability to develop new reagents for use in in vivo imaging studies of the human islet, to develop fingerprinting assays for use in predicting human islet transplant success, and to further develop cellular therapies for potential use in the treatment of type 1 diabetes.
Link to Full Grant Announcement: http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-03-021.html http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-03-021.html
Grant Announcement Contact: If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster FBOWebmaster@OD.NIH.GOV NIH OER Webmaster
Similar Government Grants: • Pediatric Centers of Excellence in Nephrology (P50); • Nutrition Obesity Research Centers (P30); • George M. OBrien Kidney Research Core Centers (P30); • Cooperative Study Group for Autoimmune Disease Prevention (U01); • Collaborative Interdisciplinary Team Science in NIDDK Research Areas (R24); • PROTEOMIC AND METABOLOMIC APPROACHES TO DIAGNOSE DIABETES AND PRE-DIABETES; • MOLECULAR THERAPY CORE CENTERS; • DIABETES ENDOCRINOLOGY RESEARCH CENTERS; • CYSTIC FIBROSIS RESEARCH AND TRANSLATION CORE CENTERS; • BETA CELL BIOLOGY CONSORTIUM (U19)