Pilot Clinical Trials in the Epidemiology, Prevention and Treatment of Respiratory Failure in Children
The summary for the Pilot Clinical Trials in the Epidemiology, Prevention and Treatment of Respiratory Failure in Children Federal Grant is detailed below.
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Federal Grant Title:
PILOT CLINICAL TRIALS IN THE EPIDEMIOLOGY, PREVENTION AND TREATMENT OF RESPIRATORY FAILURE IN CHILDREN
State governments County governments City or township governments Special district governments Independent school districts Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Individuals For profit organizations other than small businesses Small businesses Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility
Information not provided
The National Institute of Child Health and Human Development (NICHD) and the National Institute of Nursing Research (NINR) solicit applications for clinical studies designed to enhance understanding and prevention and treatment of respiratory failure in children. The present clinical literature documents the efficacy of various treatment modalities, including mechanical ventilation strategies employing conventional and innovative techniques, over a wide range of parameters, manipulated with both invasive and non-invasive maneuvers. Survival of children mechanically ventilated for a wide variety of indications is now the rule. This RFA solicits clinical studies to 1) define and characterize acute and chronic respiratory failure of various etiologies in children; 2) develop new approaches to prevent the development of chronic functional disability in children who have been mechanically ventilated for any cause; and 3) ameliorate the effects of mechanical ventilation on child development (cognitive and interpersonal), cardiovascular stability, pulmonary function, and integration into school and home care. A separate RFA solicits basic and clinical research specifically addressing the problem of improving outcomes after childhood cardiopulmonary arrest, specifically, the effects of choice, timing and duration and intensity of therapies on functional outcomes.