Pathophysiology of Bisphosphonates-associated Osteonecrosis of the Jaw (R01)

The summary for the Pathophysiology of Bisphosphonates-associated Osteonecrosis of the Jaw (R01) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.
Pathophysiology of Bisphosphonates-associated Osteonecrosis of the Jaw (R01): -This funding opportunity will utilize the NIH Individual Research Project Grant (R01) mechanism, but runs in parallel with two Funding Opportunity Announcements (FOAs) of identical scientific scope, PA-06-501 that solicits applications under the Exploratory/Developmental Grant (R21) mechanism, and PA-06-502 that solicits applications under the Small Research Grant (R03) mechanism. -Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received. -Eligible organizations include for-profit and non-profit organizations, public or private institutions such as universities, colleges, hospitals and laboratories, units of State and local governments including tribal governments, eligible agencies of the Federal government, domestic or foreign institutions/organizations, or faith-based or community-based organizations, Indian/Native American Tribal Government (Federally Recognized), Indian/Native American Tribal Government (Other than Federally Recognized), and Indian/Native American Tribally Designated Organizations.
Federal Grant Title: Pathophysiology of Bisphosphonates-associated Osteonecrosis of the Jaw (R01)
Federal Agency Name: National Institutes of Health
Grant Categories: Health Education
Type of Opportunity: Discretionary
Funding Opportunity Number: PA-06-500
Type of Funding: Grant
CFDA Numbers: 93.12193.395
CFDA Descriptions: Oral Diseases and Disorders Research 93.395 Cancer Treatment Research
Current Application Deadline: No deadline provided
Original Application Deadline: Multiple Receipt Dates - See Link to Full Announce
Posted Date: Jul 31, 2006
Creation Date: Dec 07, 2006
Archive Date: Feb 03, 2007
Total Program Funding:
Maximum Federal Grant Award: $250,000
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching: 93.846 -- Arthritis, Musculoskeletal and Skin Diseases Research
Applicants Eligible for this Grant
County governments Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities City or township governments State governments Native American tribal governments (Federally recognized) Others (see text field entitled "Additional Information on Eligibility" for clarification) Independent school districts Public and State controlled institutions of higher education For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Private institutions of higher education
Additional Information on Eligibility
Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply. Projects must focus on studying oral bone homeostasis, healing response or repair capacity in the presence or absence of bisphosphonates rather than on the broad effects of bisphosphonates on bone quality. Projects that examine the effects of bisphosphonates on skeletal biology will not be considered unless the experimental design includes analysis of oral bones. Projects may study the effects of bisphosphonates on other physiological processes such as angiogenesis but only within the context that perturbation of these processes may compromise oral bone homeostasis and healing. Projects that examine the pharmacology of bisphosphonates will be considered non-responsive unless the projects propose to test whether genetic variations alter the pharmacokinetics or pharmacodynamics of bisphosphonates. Epidemiological studies are non-responsive.
Link to Full Grant Announcement
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