Pilot Clinical Trials in the Epidemiology, Prevention and Treatment of Respiratory Failure in Children

The summary for the Pilot Clinical Trials in the Epidemiology, Prevention and Treatment of Respiratory Failure in Children grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Pilot Clinical Trials in the Epidemiology, Prevention and Treatment of Respiratory Failure in Children: The National Institute of Child Health and Human Development (NICHD) and the National Institute of Nursing Research (NINR) solicit applications for clinical studies designed to enhance understanding and prevention and treatment of respiratory failure in children. The present clinical literature documents the efficacy of various treatment modalities, including mechanical ventilation strategies employing conventional and innovative techniques, over a wide range of parameters, manipulated with both invasive and non-invasive maneuvers. Survival of children mechanically ventilated for a wide variety of indications is now the rule. This RFA solicits clinical studies to 1) define and characterize acute and chronic respiratory failure of various etiologies in children; 2) develop new approaches to prevent the development of chronic functional disability in children who have been mechanically ventilated for any cause; and 3) ameliorate the effects of mechanical ventilation on child development (cognitive and interpersonal), cardiovascular stability, pulmonary function, and integration into school and home care. A separate RFA solicits basic and clinical research specifically addressing the problem of improving outcomes after childhood cardiopulmonary arrest, specifically, the effects of choice, timing and duration and intensity of therapies on functional outcomes.