Prioritizing Molecular Targets for Cancer Prevention with Nutritional Combinations (R01)

The summary for the Prioritizing Molecular Targets for Cancer Prevention with Nutritional Combinations (R01) Federal Grant is detailed below. It contains information such as the Catalog of Federal Domestic Assistance (CFDA) number, the government agency offering the grant, funding award amounts, and important deadlines. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed in the Grant Announcement Contact section.

Federal Grant Title:	Prioritizing Molecular Targets for Cancer Prevention with Nutritional Combinations (R01)
CFDA Number:	93.393
CFDA Description:	Cancer Cause and Prevention Research
Federal Agency Name:	National Institutes of Health
Category of Funding Activity:	Education Health
Category Explanation:	Information not provided
Opportunity Category:	Discretionary
Funding Opportunity Number:	PA-10-035
Document Type:	Grants Notice
Funding Instrument Type:	Grant
Posted Date:	Nov 24, 2009
Creation Date:	Nov 24, 2009
Original Closing Date for Applications:	Jan 07, 2013
Current Closing Date for Applications:	Jan 07, 2013
Archive Date:	Feb 07, 2013
Expected Number of Awards:	Information not provided
Estimated Total Program Funding:	Information not provided
Federal Grant Award Ceiling:	Information not provided
Federal Grant Award Floor:	Information not provided
Cost Sharing or Matching Requirement:	No

Applicants Eligible for this Grant: State governments - Public and State controlled institutions of higher education - Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession.
Grant Description: Purpose. This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), and the Office of Dietary Supplements (ODS), of the National Institutes of Health (NIH), invites research applications to enhance our understanding about the dynamic interrelationship that exists between bioactive food components (and/or combinations thereof) and cancer prevention. Although much evidence exists that dietary components are linked to cancer prevention, the interactions among dietary bioactive compounds and food combinations remains under-investigated. Applications are encouraged to consider either multiple dietary bioactive components, intact foods or multiple foods utilizing physiologically relevant concentrations of the agents. New genetic technologies may be employed to study the impact of dietary components on complex cellular and molecular networks, as part of the effort to better understand the basis for the multifaceted interactions of food components with cancer prevention mechanisms. Specifically, applications that apply new high-throughput genomic, epigenomic, proteomic, and metabolomic technologies to prioritize molecular targets of dietary components are highly encouraged. The sites of action that may be evaluated include carcinogen metabolism, DNA repair, cell proliferation, apoptosis, differentiation, hormonal regulation, energetics, inflammation, and/or angiogenesis. In addition, applications should either evaluate multiple molecular targets within a cancer process or multiple processes in order to prioritize which process(es) is/are most involved in bringing about a phenotypic change. It is hoped that advances in this area may assist in optimizing cancer prevention while minimizing potential toxicity due to food components. The resulting information will help define which foods or food components should be considered in isolation or in combination when developing dietary strategies to reduce cancer risk and/or modify tumor behavior. Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism. Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.
Link to Full Grant Announcement: http://grants.nih.gov/grants/guide/pa-files/pa-10-035.html
Grant Announcement Contact: NIH OER WebmasterFBOWebmaster@OD.NIH.GOV If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster [FBOWebmaster@OD.NIH.GOV]
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