Basic Research in the Bladder and Lower Urinary Tract (R21)

The summary for the Basic Research in the Bladder and Lower Urinary Tract (R21) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Basic Research in the Bladder and Lower Urinary Tract (R21): The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Cancer Institute (NCI), and the National Institute on Aging (NIA), in cooperation with the National Institutes of Health (NIH) Office of Research on Women's Health (ORWH), invite applications for research studies which focus on basic cellular, molecular, genetic and developmental mechanisms of the normal and abnormal function of the bladder and lower urinary tract. An important goal of this initiative is to attract new and established investigators from a variety of basic science research areas to apply their knowledge, skills, and tools to studies of the bladder and lower urinary tract. -Areas of special interest include, but are not restricted to, basic cellular biology of bladder epithelial and smooth muscle cells and connective tissues; organ innervation, vascularization, immunobiology, and physiology; genomics and proteomics, including studies of age-related changes in gene expression; development of animal models; pathogen-host interactions in infectious conditions of the bladder; developmental biology of the lower urinary tract including sex differences, and age-related changes in bladder and lower urinary tract biology that affect function; and studies addressing the role of the bladder microenvironment (stroma) in bladder carcinogenesis and progression. Studies proposing the development and application of novel tools and technologies including methods of in vivo functional assessment and imaging are encouraged. Also, basic science studies addressing sex/gender differences that may predispose women to bladder and lower urinary tract disorders are encouraged. Another important goal is to promote productive research collaborations for study of the lower urinary tract between clinicians and basic scientists. This funding opportunity is presented as part of the ongoing commitment of the NIDDK, NCI, NIA, and ORWH, to biomedical research aimed at improving bladder and lower urinary tract health. -This funding opportunity will utilize the National Institutes of Health (NIH) Exploratory/Developmental (R21) award mechanism, but will be run in parallel with a funding opportunity of identical scientific scope (PA-06-254) that will utilize the traditional research project grant (R01) -Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received. -Project Period and Award Levels: The applicant may request a project period of up to two years with a combined budget for direct costs of up to $275,000 for the two-year period. -Eligible organizations include: For-profit or non-profit organizations; Public or private institutions, such as universities, colleges, hospitals, and laboratories; Units of State and local governments; Eligible agencies of the Federal government ; Domestic; and Foreign. -Eligible Project Directors/Principal Investigators (PD/PIs): Any individual with the skills, knowledge and resources necessary to carry out the proposed research, is invited to work with his/her institution to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support. -Applicants may submit more than one application, provided they are scientifically distinct. -An R21 is not renewable.