Biological Response Indicators of Environmental Stress Centers (U54)

The summary for the Biological Response Indicators of Environmental Stress Centers (U54) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Biological Response Indicators of Environmental Stress Centers (U54): -These Centers represent one part of a comprehensive program that develops and refines panels of biomarkers and biosensors of biological response to environmental stressors. By measuring the cellular, molecular and physiologic responses to environmental stressors in key physiologic and pathophysiologic pathways, the relationships between genetic and non-genetic factors that contribute to disease will be better defined. This program will focus on a product-driven approach for the development, confirmation, and application of innovative biomarkers and biosensors, especially those with potential for scale-up for use in large population studies. -The total amount of funding to be committed to this program is $18 million (total costs) over 4 years. Each year $4.5 million will be awarded. -Anticipated number of awards: 4

Federal Grant Title:	Biological Response Indicators of Environmental Stress Centers (U54)
Federal Agency Name:	National Institutes of Health
Grant Categories:	Environment Health
Type of Opportunity:	Discretionary
Funding Opportunity Number:	RFA-ES-06-012
Type of Funding:	Cooperative Agreement
CFDA Numbers:	93.113
CFDA Descriptions:	Biological Response to Environmental Health Hazards
Current Application Deadline:	No deadline provided
Original Application Deadline:	Dec 23, 2006
Posted Date:	Sep 28, 2006
Creation Date:	Sep 29, 2006
Archive Date:	Jan 22, 2007
Total Program Funding:	$4,500,000
Maximum Federal Grant Award:	$825,000
Minimum Federal Grant Award:
Expected Number of Awards:	4
Cost Sharing or Matching:	No

Applicants Eligible for this Grant: County governments Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal governments (Federally recognized) Others (see text field entitled "Additional Information on Eligibility" for clarification) City or township governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Private institutions of higher education
Additional Information on Eligibility: Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply. In order to be considered for peer review and funding, the U54 Centers must have a minimum of three highly meritorious research projects, must include an Administrative Core, and can have one or more highly meritorious facility cores that meet the general description laid out in Section I, General Characteristics of a U54 Exposure Biology Center. The applicant must name a Center Director who commits a minimum of 10% to Center leadership and administration. At least one research project must include research involving human specimens. Milestones All applications must include a specific section labeled Milestones for each year. Milestones should be annual, well-described, quantitative, and scientifically justified and not simply a restatement of the specific aims. Rather, the milestones should offer a timeline and a pathway for the development of the proposed technology. These milestones will be used to judge the success of the proposed research on an individual-project basis. It is expected that the milestones will be adjusted annually at the award anniversary dates to incorporate the group's scientific accomplishments and progress and to reflect any recommendations of the Steering and Advisory Committees. Meetings The Exposure Biology Program investigators will be expected to attend Steering Committee meetings two times per year and participate in monthly conference calls to discuss their research progress. Funds to support travel of the key investigators to attend these meetings should be included in the application budget.
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