Computational Toxicology and Endocrine Disruptors: Use of Systems Biology in Hazard Identification and Risk Assessment

The summary for the Computational Toxicology and Endocrine Disruptors: Use of Systems Biology in Hazard Identification and Risk Assessment grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the Environmental Protection Agency, which is the U.S. government agency offering this grant.
Computational Toxicology and Endocrine Disruptors: Use of Systems Biology in Hazard Identification and Risk Assessment: The U.S. Environmental Protection Agency (EPA), through its Science to Achieve Results (STAR) program, is seeking applications proposing innovative approaches for incorporating computational methods into hazard identification and risk assessment. These proposals should incorporate a systems biology approach with chemical effects assessment using traditional and novel techniques, which could include genomics, proteomics, and metabonomics. The proposals should focus on one, or both, of the following investigational areas: 1) Development of integrative, quantitative models of the function of the hypothalamic-pituitary-gonadal or hypothalamic-pituitary-thyroid axes with emphasis on the descriptions of the normal physiological processes and mechanisms of perturbation following exposure to xenobiotics (e.g., endocrine disrupting chemicals), in rats or a commonly used small fish toxicology model (e.g., fathead minnow, medaka, zebrafish). (2) Cross-species extrapolation of integrative, quantitative models of the perturbed hypothalamic-pituitary-gonadal or hypothalamic-pituitary-thyroid axes following exposure to xenobiotics from rats to humans or a commonly used small fish toxicology model (e.g., fathead minnow, medaka, zebrafish) to other vertebrates (i.e., within the same class or across classes). The cross-species extrapolation should be based on models as described in item (1). Proposals should demonstrate the existence of these models and their validity.
Federal Grant Title: Computational Toxicology and Endocrine Disruptors: Use of Systems Biology in Hazard Identification and Risk Assessment
Federal Agency Name: Environmental Protection Agency
Grant Categories: Environment
Type of Opportunity: Discretionary
Funding Opportunity Number: EPA-GRANTS-102303-003
Type of Funding: Grant
CFDA Numbers: 66.509
CFDA Descriptions: Science To Achieve Results (STAR) Program
Current Application Deadline: No deadline provided
Original Application Deadline: Jan 21, 2004 The deadline for receipt of the appl
Posted Date: Oct 23, 2003
Creation Date: Feb 20, 2004
Archive Date: Feb 20, 2004
Total Program Funding:
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching: No
Applicants Eligible for this Grant
State governments County governments City or township governments Special district governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Individuals
Link to Full Grant Announcement
Information not provided
Grant Announcement Contact
Francis, Elaine, Project Officer, Phone 202-564-6789, Email [email protected] [email protected] Francis, Elaine
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