Department of Defense (DOD) Neurofibromatosis Research Program (NFRP) Investigator Initiated Research Award

The summary for the Department of Defense (DOD) Neurofibromatosis Research Program (NFRP) Investigator Initiated Research Award grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the Dept of the Army USAMRAA, which is the U.S. government agency offering this grant.

Department of Defense (DOD) Neurofibromatosis Research Program (NFRP) Investigator Initiated Research Award: The Neurofibromatosis Research Program (NFRP) Investigator-Initiated Research Award supports basic and clinically oriented research that will (1) provide insight into the development of NF and related diseases, (2) result in substantial improvements over todays approach to the diagnosis and treatment of neurofibromatosis and/or Schwannomatosis, (3) enhance the quality of life of persons with those diseases. Proposals must include preliminary data relevant to NF research and the proposed project. In addition, if appropriate, a clear statistical plan of analysis should be included. The fiscal year 2007 (FY07) NFRP encourages proposals that specifically address critical needs of the NF community in the following areas (please note that these have been revised since FY06): . Translational research such as the development or preclinical testing of therapeutic agents for the treatment of neurofibromatosis; . Complications of neurofibromatosis with high mortality such as childhood neoplasms, malignant peripheral nerve sheath tumors, and cerebrovascular abnormalities; . Complications of neurofibromatosis with high morbidity such as skeletal maladies, learning deficits, hormone-associated effects, and pain; . Refinement and standardization of imaging techniques for use in future clinical trials. Proposals including Clinical Trials: If a proposal requests support for a clinical trial, the Principal Investigator (PI) is required to submit a clinical protocol in addition to the proposal by the proposal receipt deadline. Guidelines for protocol preparation are outlined in Appendix 7. The protocol will be reviewed separately. Optional Collaborator (new this year): The FY07 NFRP strongly supports collaborative research between basic scientists and clinical researchers and between academic scientists and industry scientists. Collaborations that bring new perspectives from other disciplines or bring new investigators into the NF field are also strongly encouraged. These types of collaborations will qualify for a higher level of funding as described in Section II.C. Proposals requesting the higher level of funding must meet the following criteria: . The collaborator must significantly contribute to the project such that the proposed work could not be accomplished without his/her involvement. . If the PI of the proposal does not have NF research experience, the collaborator must have experience in NF research as demonstrated through publications and/or funding history. . The collaborator must be at or above the level of Assistant Professor (or equivalent). . At least a 10% level of effort is required of the collaborator. Contribution of the collaborator should be reflected in the proposal's budget.