Diet-Induced Changes in Inflammation as Determinants of Colon Cancer

The summary for the Diet-Induced Changes in Inflammation as Determinants of Colon Cancer grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Diet-Induced Changes in Inflammation as Determinants of Colon Cancer: - Inflammation is a natural response of the human body to tissue injury or infection, but can, in some normal and abnormal conditions, be acute or chronic and result in serious complications, including colon cancer. The various checks and balances within the inflammatory process may be compromised by the quantity and duration of the insult, or by a host of genetic and environmental factors including diet. Several epidemiological and pre-clinical studies reveal that specific bioactive food components can suppress colonic inflammation as well as reduce colon cancer risk. Nevertheless, it remains unclear whether these diet-induced shifts in the inflammatory process account for their anti-tumorigenic properties in colon cancer. This PA is designed to foster innovative research that will identify and characterize diet-induced changes in inflammation and colon cancer risk. - Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the numbers, qualities, durations, and costs of the applications received. - This funding opportunity will use the NIH investigator-initiated research project grants (R01) and exploratory/developmental (R21) award mechanisms. - You may submit (an) application(s) if your institution has any of the following characteristics: for-profit organizations; non-profit organizations; public or private institutions, such as universities, colleges, hospitals, and laboratories; units of State and local governments; eligible agencies of the Federal government; domestic institutions; foreign institutions; faith-based or community-based organizations; Units of State Tribal government; and Units of Local Tribal government. - Any individual with the skills, knowledge, and resources necessary to carry out the proposed research is invited to work with their institution to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH programs. - See Section IV.1 for application materials. - Applicants may submit more than one application, provided they are scientifically distinct. - Telecommunications for the hearing impaired is available at: TTY 301-451-0088.