DoD Lung Cancer Clinical Exploration Award

The summary for the DoD Lung Cancer Clinical Exploration Award grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the Dept of the Army USAMRAA, which is the U.S. government agency offering this grant.
DoD Lung Cancer Clinical Exploration Award: The LCRP CEA mechanism was first offered in FY13. Since then, 35 CEA applications have been received, and 5 have been recommended for funding. This award mechanism supports early-phase, proof-of-principle clinical trials and correlative studies to investigate hypothesis-based, innovative interventions that have the potential to resolve current clinical barriers and result in a profound impact on the clinical management of lung cancer. While therapeutic approaches proposed for testing through the CEA must represent novel, hypothesis-based, “outside-the-box” approaches for treating lung cancer, they may include therapies already in clinical use, or undergoing clinical testing for other diseases, provided that the proposed use for lung cancer would lead to a major advancement for treating the disease. Outcomes from studies funded by this award are anticipated to provide scientific rationale for subsequent development of larger, efficacy-based clinical trials of interventions that will transform lung cancer clinical care. Submissions from and partnerships with investigators at military treatment facilities, military labs, and Department of Veterans Affairs (VA) medical centers and research laboratories are strongly encouraged.

Clinical Trials Category: The CEA supports clinical trials encompassing Phase 0, Phase I, or pilot Phase II for drug or drug combinations, Class II or III devices, or other types of trials that conduct early clinical testing of innovative approaches for lung cancer. Information on clinical trials and phases/classes of study is provided in the “Human Subject Resource Document” available for download from eBRAP at https://ebrap.org/eBRAP/public/Program.htm.

Correlative Studies Category: The CEA-Correlative Studies category supports innovative, hypothesis-based, correlative studies that derive from ongoing or completed clinical trials supported by other funding sources. These correlative studies, if successful, will have the potential to significantly inform treatment strategies, identify subsets of patients for treatment with specific therapies, provide increased understanding of biological changes resulting from the intervention in lung cancer, or provide other insight that will significantly enhance clinical management of lung cancer. Examples of correlative studies appropriate for submission to the CEA-Correlative Studies category may include, but are not limited to:
• Analysis of biomarkers for prognosis and/or prediction or assessment of therapeutic response or progression
• Investigations of the mechanism of action or the development of resistance to a drug
• Analysis of immune response or factors associated with progression
• Characterization of tumor antigens for the development of new improved therapies
Federal Grant Title: DoD Lung Cancer Clinical Exploration Award
Federal Agency Name: Dept of the Army USAMRAA
Grant Categories: Science and Technology
Type of Opportunity: Discretionary
Funding Opportunity Number: W81XWH-15-LCRP-CEA
Type of Funding: Cooperative Agreement, Grant
CFDA Numbers: 12.420
CFDA Descriptions: Military Medical Research and Development
Current Application Deadline: Sep 16, 2015
Original Application Deadline: Sep 16, 2015
Posted Date: Apr 8, 2015
Creation Date: Apr 8, 2015
Archive Date: Oct 16, 2015
Total Program Funding: $2,240,000
Maximum Federal Grant Award: none
Minimum Federal Grant Award: none
Expected Number of Awards: 4
Cost Sharing or Matching: No
Applicants Eligible for this Grant
Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Grant Announcement Contact
Phone: (301) 682-5507 Email: [email protected]
CDMRP Help Desk

Dept. of the Army -- USAMRAA 301-619-7144
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