Effects of Long Term Use of Antiretroviral Therapy on the Oral Mucosa (R21)

The summary for the Effects of Long Term Use of Antiretroviral Therapy on the Oral Mucosa (R21) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Effects of Long Term Use of Antiretroviral Therapy on the Oral Mucosa (R21): -The purpose of this Initiative is to stimulate research on the long term effects of antiretroviral therapy (ART) on, for example, the qualitative and quantitative composition of the saliva, innate and adaptive immune networks of the oral mucosa, and oral epithelial structures and functions. Such research will provide valuable insight into the cellular and molecular mechanisms responsible for occurrence or re-occurrence of oral disorders in HIV infected/AIDS patients, despite having been treated with ART. A goal of the initiative is to identify novel strategies for prevention and management of oral manifestations of HIV infection and AIDS by reducing the negative effects of ART. -Up to $700,000 total cost (Direct costs plus Facilities and Administrative costs) may be awarded in support of this solicitation -Up to three new grants are anticipated to be funded. -This FOA will use the NIH exploratory/development research grant (R21) award mechanism. -Eligible organizations include: For-profit or non-profit organizations, public or private institutions, such as universities, colleges, hospitals, and laboratories, units of State and local governments, eligible agencies of the Federal government, domestic institutions/organizations, and foreign institutions that offer unusual talent, resources, populations, or environmental conditions that are not readily available in the United States or that augment existing U.S. resources. -Eligible principal investigators include any individual with the skills, knowledge, and resources necessary to carry out the proposed research. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH programs. -Investigators may submit more than one application. There should be no scientific or budgetary overlap.