Genomics of Transplantation Cooperative Research Program

The summary for the Genomics of Transplantation Cooperative Research Program grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Genomics of Transplantation Cooperative Research Program: The purpose of this RFA is to solicit applications from single institutions or consortia of institutions to establish cooperative interdisciplinary research programs for large-scale, broad-scope genomic studies in clinical transplantation, including solid organ, tissue, and cell transplantation. The goals of this program are to identify and characterize gene polymorphisms and gene expression patterns that: (1) correlate with and/or predict transplantation outcomes; (2) delineate immune responses relating to the onset and severity of acute and chronic graft rejection; (3) predict responses to immunosuppressive therapeutics to allow tailoring of therapy; and (4) elucidate the genetic basis of variability in graft survival between populations. The long-term goal of the program is to understand the genetic basis of immune-mediated graft rejection and differences in transplant outcomes, and thereby provide a rational basis for the development of more effective treatment and prevention strategies to improve long-term graft survival and provide a better quality-of-life for transplant recipients.