In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk (R01)

The summary for the In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk (R01) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.
In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk (R01): -Purpose. This Funding Opportunity Announcement (FOA) solicits innovative preclinical applications that propose research that will enhance the understanding of the relationship between exposures to bioactive food components and/or environmental chemicals in utero, hormonal and growth-factor response, gene expression or epigenetic changes, and subsequent mammary cancer risk in preclinical models. Although much evidence suggests that dietary components are linked to cancer prevention, the specific nutrients, sites of action, and role of exposure in utero remain elusive. Similarly, there are data suggesting a role for environmental agents such as mycotoxins, heterocyclic amines, and environmental chemicals with endocrine activity in the etiology of mammary cancer but the doses, windows of susceptibility, and mechanisms are unclear. This FOA encourages applications that apply new high-throughput genomic, epigenomic, proteomic, and metabolomic technologies to determine how dietary exposures in utero influence adult breast cancer susceptibility. The resulting information will help define effective maternal dietary intervention strategies for breast cancer prevention in her offspring. -Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism and runs in parallel with an FOA of identical scientific scope, PA-06-277, that solicits applications under the Exploratory/Developmental Grant (R21) award mechanism. -Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.
Federal Grant Title: In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk (R01)
Federal Agency Name: National Institutes of Health
Grant Categories: Health Environment Education
Type of Opportunity: Discretionary
Funding Opportunity Number: PA-07-178
Type of Funding: Grant
CFDA Numbers: 93.11393.393
CFDA Descriptions: Environmental Health 93.393 Cancer Cause and Prevention Research
Current Application Deadline: No deadline provided
Original Application Deadline: Multiple Receipt Dates - See Link to Full Announce
Posted Date: Dec 15, 2006
Creation Date: Apr 10, 2008
Archive Date: May 11, 2008
Total Program Funding:
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching: 93.396 -- Cancer Biology Research
Applicants Eligible for this Grant
For profit organizations other than small businesses Small businesses State governments Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education County governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled "Additional Information on Eligibility" for clarification) City or township governments Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts
Additional Information on Eligibility
Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply.
Link to Full Grant Announcement
Information not provided
Grant Announcement Contact
NIH OER Webmaster
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