Integration of Mouse Models into Human Cancer Research (U01)

The summary for the Integration of Mouse Models into Human Cancer Research (U01) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Integration of Mouse Models into Human Cancer Research (U01): urpose. This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), extends the NCI-Mouse Models of Human Cancers Consortium (NCI-MMHCC) for a third project period. The previous periods resulted in generation, validation, and utilization of many novel mouse cancer models. Having successfully attained the original specific program goals, the NCI-MMHCC is poised to enter the next stage that stresses the use of biologically relevant mouse models as effective tools for human research. The overall objective of the NCI-MMHCC is integration of mouse models into basic, translational, epidemiological, and clinical cancer research. Goal 1 of the NCI-MMHCC is to support individual research projects that promote innovation in use of mouse models to address crucial questions in human cancer research. All applicants who respond to this FOA must submit applications for regular research project awards that address Goal 1. To facilitate the overall research and integration goals, the NCI-MMHCC will also support up to four Science Leadership components to coordinate activities in defined scientific areas ( research clusters ) under Goal 2 Science Leadership and Integration . Goal 2 includes (a) coordinating intra-NCI-MMHCC projects in specific research clusters; (b) enhancing collaborations throughout the NCI-MMHCC and with NCI networks and consortia; and (c) expanding the NCI cancer models bioinformatics infrastructure and integrating it with human cancer bioinformatics. The Science Leadership components must be based on the science of appropriate research projects. Therefore, only applicants who submit research project applications may also submit separate applications for Science Leadership components to serve Goal 2.