Joint Degeneration: Mouse Models
The summary for the Joint Degeneration: Mouse Models grant is detailed below.
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Joint Degeneration: Mouse Models: This announcement solicits proposals of research employing genetically defined and genetically modified mouse models to explore the biological mechanisms underlying non-inflammatory joint degeneration, or osteoarthritis. Inflammatory processes are evident in late stages of osteoarthritis, and are likely to be major contributors to the chronic pain that is the most common symptom of the condition. However, for the purpose of this initiative, osteoarthritis is distinguished from diseases, such as rheumatoid arthritis, in which inflammation arising from autoimmunity is the primary cause of tissue damage. In contrast, the root causes of joint degeneration in osteoarthritis remain unclear. Increasing knowledge of molecular mechanisms in cartilage and bone biology, along with advances in the genetic manipulation of mice, have yielded new concepts and new animal models that may be relevant to osteoarthritis in humans. This Program Announcement is intended to accelerate the characterization of new models and the testing of hypotheses that could lead to improved diagnosis and treatment of osteoarthritis.
Federal Grant Title: | Joint Degeneration: Mouse Models |
Federal Agency Name: | National Institutes of Health |
Grant Categories: | Health |
Type of Opportunity: | Discretionary |
Funding Opportunity Number: | PA-04-139 |
Type of Funding: | Grant |
CFDA Numbers: | 93.12193.846 |
CFDA Descriptions: | Oral Diseases and Disorders Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research |
Current Application Deadline: | No deadline provided |
Original Application Deadline: | Multiple Receipt Dates - See Link to Full Announce |
Posted Date: | Aug 16, 2004 |
Creation Date: | Jun 09, 2006 |
Archive Date: | Jun 02, 2006 |
Total Program Funding: | |
Maximum Federal Grant Award: | $200,000 |
Minimum Federal Grant Award: | |
Expected Number of Awards: | |
Cost Sharing or Matching: | 93.866 -- Aging Research |
- Applicants Eligible for this Grant
- Public and State controlled institutions of higher education Others (see text field entitled "Additional Information on Eligibility" for clarification) State governments Independent school districts Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments County governments For profit organizations other than small businesses Special district governments Native American tribal governments (Federally recognized)
- Additional Information on Eligibility
- Eligible agencies of the Federal Government
- Link to Full Grant Announcement
- Information not provided
- Grant Announcement Contact
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