NIH Directors New Innovator Award Program (DP2 Clinical Trial Optional)

The summary for the NIH Directors New Innovator Award Program (DP2 Clinical Trial Optional) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

NIH Directors New Innovator Award Program (DP2 Clinical Trial Optional): The NIH Directors New Innovator Award Program supports early stage investigators of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. For the program to support the best possible researchers and research, applications are sought which reflect the full diversity of the research workforce. To support innovative and novel research across the vast NIH mission, individuals from diverse backgrounds (including those from underrepresented groups; see Notice of NIHs Interest in Diversity) and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply to this Notice of Funding Opportunity. Applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. The NIH Director's New Innovator Award Program complements other ongoing efforts by NIH and its Institutes and Centers to fund early stage investigators. The NIH Directors New Innovator Award Program is a component of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund.

Federal Grant Title:	NIH Directors New Innovator Award Program (DP2 Clinical Trial Optional)
Federal Agency Name:	National Institutes of Health (HHS-NIH11)
Grant Categories:	Health
Type of Opportunity:	Discretionary
Funding Opportunity Number:	RFA-RM-25-002
Type of Funding:	Grant
CFDA Numbers:	93.310
CFDA Descriptions:	Information not provided
Current Application Deadline:	August 19th, 2025
Original Application Deadline:	August 19th, 2025
Posted Date:	June 12th, 2025
Creation Date:	June 12th, 2025
Archive Date:	September 24th, 2025
Total Program Funding:
Maximum Federal Grant Award:	$475,000
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching:	No
Last Updated:	June 13th, 2025

Applicants Eligible for this Grant: State governments - County governments - City or township governments - Special district governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Public housing authorities/Indian housing authorities - Native American tribal organizations (other than Federally recognized tribal governments) - Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For-profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification.)
Additional Information on Eligibility: Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Link to Full Grant Announcement: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-25-002.html
Grant Announcement Contact: NIH Grants Information
[email protected]
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Similar Government Grants: • Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Acces...; • NIH Directors Transformative Research Awards (R01 Clinical Trial Optional); • NIH Directors Pioneer Award Program (DP1 Clinical Trial Optional); • Complement-ARIE New Approach Methodologies (NAMs) Data Hub and Coordinating Center (U24 Cl...; • Complement-ARIE New Approach Methodologies (NAMs) Technology Development Centers (UM1 Clin...; • Using Metabolomics to Investigate Biological Pathways and Networks (R01); • Assay Development for High Throughput Molecular Screening (R21); • Membrane Protein Production and Structure Determination (R01)
More Grants from the National Institutes of Health: • Single Source: National Centralized Repository for Alzheimer's Disease and Related Dementi...; • Tobacco Regulatory Science Small Grant Program for New Investigators (R03 Clinical Trial O...; • Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Acces...; • Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed...; • Limited Competition: Regenerative Medicine Innovation Project (RMIP) Investigator-Initiate...