Pathogenesis and Treatment of Lymphedema and Lymphatic Diseases

The summary for the Pathogenesis and Treatment of Lymphedema and Lymphatic Diseases grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Pathogenesis and Treatment of Lymphedema and Lymphatic Diseases: The National Heart, Lung, and Blood Institute (NHLBI), National Institute of Child Health and Human Development (NICHD), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Cancer Institute (NCI), National Institute of Nursing Research (NINR), National Center for Complementary and Alternative Medicine (NCCAM), and National Institute on Biomedical Imaging and Bioengineering (NIBIB) invite qualified researchers to submit applications for research project grants to investigate the pathogenesis and new treatments for primary and secondary lymphedema. The purpose of this program announcement is to stimulate research on the biology of the lymphatic system, to characterize at the molecular, cellular, tissue, organ, and intact organism levels, the pathophysiologic mechanisms that cause the disease, to develop new methods for quantitating and imaging lymph flow, to discover new therapeutic interventions, and to determine the safety, efficacy and mechanisms of action of complementary and alternative therapies. The scope of this research includes developmental biology and genetics of the lymphatic system to identify and characterize genes important for its organization and regulation. Such knowledge will help to improve early diagnosis of affected individuals, the choice and timing of treatment, and genetic counseling. Research is also needed on the pathophysiology of the disorders of skin and subcutaneous tissue secondary to chronic lymphedema, and lymphedema which results from cancers and cancer treatment, with an ultimate goal to develop more targeted and effective therapies.