Preventing Mitochondrial Oxidative Stress in Diabetes and Obesity

The summary for the Preventing Mitochondrial Oxidative Stress in Diabetes and Obesity grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.
Preventing Mitochondrial Oxidative Stress in Diabetes and Obesity: - Hyperglycemia is a significant causative factor for the complications of diabetes mellitus, which results in significant morbidity and mortality for millions of Americans. Recent advances on the cellular effects of hyperglycemia places the overproduction of reactive oxygen species (ROS) by the mitochondrial electron transport chain as a strong candidate for the core abnormality that leads to other biochemical and cellular defects and the resulting tissue injury. The purpose of this RFA is to encourage the translation of these recent advances into therapies that can interrupt the increase in mitochondrial ROS and prevent their role in diabetic complications. - R01 and R21 applications from qualified principal investigators are invited for basic or clinical studies for discovering and characterizing molecular targets, agents and assays related to the accumulation of mitochondrial ROS secondary to hyperglycemia. - The participating institutes plan on contributing $2.5 million to fund 5-10 new awards with project periods of 2-4 years. - Non-profit or for-profit organizations are eligible, including public or private institutions and domestic and foreign institutions. - Applicants may submit more than one application, providing there is no scientific or budgetary overlap. - The PHS 398 application can be obtained from http://grants.nih.gov/grants/funding/phs398/phs398.html
Federal Grant Title: Preventing Mitochondrial Oxidative Stress in Diabetes and Obesity
Federal Agency Name: National Institutes of Health
Grant Categories: Health Education
Type of Opportunity: Discretionary
Funding Opportunity Number: RFA-DK-05-001
Type of Funding: Grant
CFDA Numbers: 93.39393.396
CFDA Descriptions: Cancer Cause and Prevention Research 93.396 Cancer Biology Research
Current Application Deadline: No deadline provided
Original Application Deadline: Feb 24, 2005
Posted Date: Nov 30, 2004
Creation Date: Nov 30, 2004
Archive Date: Mar 26, 2005
Total Program Funding: $2,500,000
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards: 5
Cost Sharing or Matching: 93.847 -- Diabetes, Endocrinology and Metabolism Research
Applicants Eligible for this Grant
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses Public and State controlled institutions of higher education Private institutions of higher education State governments County governments City or township governments Special district governments Independent school districts Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility
Eligible agencies of the Federal Government are eligible to apply. Foreign institutions are eligible to apply. Foreign institutions/organizations considering applying to this RFA must demonstrate an ability to conduct the proposed study in the designated setting(s), as well as an ability to meet government clearance requirements.
Link to Full Grant Announcement
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