Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Centers (U54)

The summary for the Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Centers (U54) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Centers (U54): -This funding opportunity announcement (FOA) solicits new (type 1) and competitive renewal (type 2) applications for the support of Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Centers. Successful applicants will join a network of existing Centers to foster the translation of new scientific findings and technological developments into novel treatments for the muscular dystrophies. Each Center may contain a mixture of basic, translational, or clinical research, as long as efforts are directed toward the steps required for therapeutic development, including therapeutic target identification, characterization, and validation, development of diagnostics and biomarkers to characterize or stratify patient populations, in vitro assay development, animal model development and characterization, candidate therapeutic efficacy screening, preclinical therapeutic optimization and FDA-required activities leading to an investigational new drug (IND) application, clinical infrastructure and studies in support of a clinical trial, patient-oriented natural history studies, and early stage clinical trials for one or more types of muscular dystrophy. -Applicants should propose multi-disciplinary and collaborative studies that address one or more gaps in the therapeutic development pipeline for muscular dystrophy. Research problems should require substantial collaborative efforts to solve, and thus are best carried out in a center setting. -Centers should be designed to include the following components: one or more scientific project(s), an Administrative Core, a Scientific Research Resource Core with national impact, and a Research Training and Education Core. Applications may include additional core facilities within the overall budget cap (see below).