Systems and Methods for Small Animal Imaging

The summary for the Systems and Methods for Small Animal Imaging grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.
Systems and Methods for Small Animal Imaging: The National Institute of Biomedical Imaging and Bioengineering (NIBIB) invites investigator-initiated applications for NIH Research Project Grant (R01) awards to support interdisciplinary basic research or Exploratory/Developmental Research (R21) awards to support novel investigations related to the development of small animal imaging devices and methods that can be applied broadly to research on diverse biological or disease processes. A companion Program Announcement related to this initiative is available at (http://grants.nih.gov/grants/guide/pa-files/PA-03-031.html) for those eligible for the Small Business Innovation Research/Small Business Technology Transfer (SBIR/STTR) program. The primary focus of this Request for Applications (RFA) is research and development related to devices, methods, and imaging agents for the investigation of biological and disease processes in small animals. The integration of systems and methods with complementary imaging and/or spectroscopy modalities is also included as appropriate to provide anatomic, physiologic, metabolic, and molecular-level information in small animal models of disease. The motivation for this RFA is that recent discoveries in genomics and molecular and cell biology have led to the development and wide use of small animal models of human disease. One of the limitations with the use of these models is the need to sacrifice large numbers of animals for ex vivo tissue and molecular analysis. Imaging instrumentation and methods that permit imaging on the scale of small animals offer an opportunity to address this problem by enabling noninvasive investigations of biological processes in vivo. This provides the potential for longitudinal studies in the same animal. This coupling of animal models of human disease with advances in imaging technology presents an extraordinary opportunity for biomedical imaging to play an important role in the early detection, diagnosis, and treatment of disease. Several dedicated small animal imaging systems have been developed and a few commercialized, although technological hurdles still exist that limit the realization of the full potential of small animal imaging for biomedical research and drug development. Progress is needed to improve throughput, sensitivity, and spatial and temporal resolution of small animal imaging devices, to provide quantitative information through improved reconstruction methods that incorporate models of physical effects, and to provide improved methods for system validation. System optimization incorporating the design of molecular probes that serve as links to particular biological processes in vivo is also a focus. Further improvements in system design, image processing and analysis software, and data sharing technology, coupled with improvements and innovations in animal handling techniques used during imaging, are needed to make small animal imaging technology more accessible to molecular biologists and pharmaceutical scientists desiring to use animal models as tools for biomedical research and drug discovery and development. The NIBIB seeks to improve health by promoting fundamental discoveries, design and development, and translation and assessment of technological capabilities in biomedical imaging and bioengineering enabled by relevant areas of physics, chemistry, mathematics, engineering, materials science, and computer science.
Federal Grant Title: Systems and Methods for Small Animal Imaging
Federal Agency Name: National Institutes of Health
Grant Categories: Health
Type of Opportunity: Discretionary
Funding Opportunity Number: RFA-EB-03-002
Type of Funding: Grant
CFDA Numbers: 93.28693.287
CFDA Descriptions: Discovery and Applied Research 93.287 Bioengineering Research
Current Application Deadline: No deadline provided
Original Application Deadline: Jan 16, 2003
Posted Date: Nov 25, 2002
Creation Date: Feb 15, 2003
Archive Date: Feb 15, 2003
Total Program Funding:
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching: No
Applicants Eligible for this Grant
State governments County governments City or township governments Special district governments Independent school districts Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Individuals For profit organizations other than small businesses Small businesses Others (see text field entitled "Additional Information on Eligibility" for clarification)
Link to Full Grant Announcement
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