The Early Detection Research Network: Clinical Epidemiology and Validation Centers
The summary for the The Early Detection Research Network: Clinical Epidemiology and Validation Centers grant is detailed below.
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The Early Detection Research Network: Clinical Epidemiology and Validation Centers: The Division of Cancer Prevention (DCP), National Cancer Institute (NCI), invites new and competing renewal cooperative agreement applications to continue the national Early Detection Research Network (EDRN) that has the responsibility for the development, evaluation, and validation of biomarkers for earlier cancer detection and risk assessment. Biomarkers are defined as cellular, biochemical, and molecular (genetic and epigenetic) alterations by which a normal, abnormal, or simply biologic process can be recognized or monitored. Biomarkers are measurable in biological media, such as in tissues, cells, or fluids. The Network has four main components : Biomarker Developmental Laboratories (BDL), Biomarker Reference Laboratories (formerly known as Biomarker Validation Laboratories), Clinical Epidemiology and Validation Centers (formerly known as Clinical and Epidemiologic Centers), and a Data Management and Coordinating Center (DMCC). The Biomarker Developmental Laboratories have responsibility for the development and characterization of new, or the refinement of existing, biomarkers and assays. The Biomarker Reference Laboratories serve as a Network resource for clinical and laboratory validation of biomarkers, which include technological development and refinement. The Clinical Epidemiology and Validation Centers collaboratively conduct clinical and epidemiological research on the Network-wide clinical validation of biomarkers. The Data Management and Coordinating Center supports statistical and computational analysis and informatics infrastructure and coordinates network-wide meetings and conferences. For further details, see http://www.cancer.gov/edrn. The EDRN Steering Committee (SC) is composed of the Principal Investigators (PIs) in the Network and appropriate NCI staff to coordinate the work of the Network. The purpose of this Request for Applications (RFA)is to invite new and competing renewal applications for the Clinical Epidemiology and Validation Centers. This RFA will allow the submission of applications involving U01 and U24 Cooperative Agreement award mechanisms. An RFA (CA-04-006) for the Biomarker Developmental Laboratories was previously published in the NIH guide on September 26, 2003. This RFA is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-04-006.html. RFAs for the Biomarker Reference Laboratories (CA-05-009) and for the Data Management and Coordinating Center will be issued in the near future. Applicants are encouraged to seek funding to participate in more than one component, because it is recognized that collaborations already exist in individual institutions for clinical testing and validation of biomarkers and reagents.
Federal Grant Title: | The Early Detection Research Network: Clinical Epidemiology and Validation Centers |
Federal Agency Name: | National Institutes of Health |
Grant Categories: | Health Education |
Type of Opportunity: | Discretionary |
Funding Opportunity Number: | RFA-CA-05-005 |
Type of Funding: | Cooperative Agreement |
CFDA Numbers: | 93.39393.394 |
CFDA Descriptions: | Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research |
Current Application Deadline: | No deadline provided |
Original Application Deadline: | Jun 14, 2004 |
Posted Date: | Jan 20, 2004 |
Creation Date: | Jul 14, 2004 |
Archive Date: | Jul 14, 2004 |
Total Program Funding: | |
Maximum Federal Grant Award: | |
Minimum Federal Grant Award: | |
Expected Number of Awards: | |
Cost Sharing or Matching: | No |
- Applicants Eligible for this Grant
- State governments County governments City or township governments Special district governments Independent school districts Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Small businesses Others (see text field entitled "Additional Information on Eligibility" for clarification)
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