The Fetal Basis of Adult Disease: Role of the Environment

The summary for the The Fetal Basis of Adult Disease: Role of the Environment grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.
The Fetal Basis of Adult Disease: Role of the Environment: This PA replaces PAR-03-121. It is recognized that between two-percent and five-percent of all live-born infants have a major developmental defect. Approximately 40 percent of these defects are thought to be due to the effect(s) of an adverse exposure of a genetically pre-disposed fetus to intra-uterine environmental factors. It is now clear that in many cases the fetus is more sensitive than the adult to the same environmental insults. Exposure to environmental agents during early development can result in death, structural malformation, and/or functional alteration of the embryo/fetus. These toxicant-induced pathogenic responses are most likely the result of altered gene expression associated with altered cell production and cell differentiation involved in the establishment of cell lineages leading to the structural and functional character of the tissues, organs, and systems that arise from these lineages. The NIEHS has a significant program that addresses the role of developmental exposures on structural malformations i.e., classical birth defects and on functional alterations whose effects are readily observable early in development. The purpose of this program announcement with a set aside of funds and a Special Emphasis Panel review by the NIH Center for Scientific Review is to stimulate research in an important and emerging area of developmental toxicology: the effects of in utero exposures that cause permanent functional changes that are not overtly, grossly teratogenic yet that result in increased susceptibility to disease/dysfunction later in the life span. This program announcement seeks to encourage the application of the new high-throughput functional-genomic, metabonomic, proteomic, and bioinformatic technologies to pursue an understanding of these latent effects of in utero environmental insult.
Federal Grant Title: The Fetal Basis of Adult Disease: Role of the Environment
Federal Agency Name: National Institutes of Health
Grant Categories: Health Environment
Type of Opportunity: Discretionary
Funding Opportunity Number: PAR-04-104
Type of Funding: Grant
CFDA Numbers: 93.11393.114
CFDA Descriptions: Biological Response to Environmental Health Hazards 93.114 Applied Toxicological Research and Testing
Current Application Deadline: No deadline provided
Original Application Deadline: Multiple Receipt Dates - See Link to Full Announce
Posted Date: May 17, 2004
Creation Date: May 17, 2004
Archive Date: Sep 12, 2004
Total Program Funding:
Maximum Federal Grant Award: $100,000
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching: No
Applicants Eligible for this Grant
State governments County governments City or township governments Special district governments Independent school districts Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Small businesses
Link to Full Grant Announcement
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