Early Detection Research Network: Clinical Validation Centers (U01)
The summary for the Early Detection Research Network: Clinical Validation Centers (U01) Federal Grant is detailed below.
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Federal Grant Title:
EARLY DETECTION RESEARCH NETWORK: CLINICAL VALIDATION CENTERS (U01)
Public and State controlled institutions of higher education - Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility
Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; U.S. Territory or Possession.
Purpose. This funding opportunity announcement (FOA) solicits cooperative agreement applications for Clinical Validation Centers (CVCs), one of the four components of the Early Detection Research Network (EDRN). EDRN is a national consortium funded to discover, develop, and validate biomarkers for early cancer detection, risk assessment and the molecular diagnosis and prognosis of early cancer. CVCs conduct clinical research on the validation of biomarkers for early cancer detection and risk assessment and serve as clinical resource centers for the EDRN by participating in collaborative biomarker validation studies and collaborating with the other components of the EDRN. The other three main components of the EDRN are: Biomarker Developmental Laboratories (BDLs), which discover, develop, and characterize new or refine existing biomarkers and assays; the Biomarker Reference Laboratories (BRLs), which serve as Network resources for clinical and laboratory validation of biomarkers; and the Data Management and Coordinating Center (DMCC), which supports statistical and computational analyses, data management, protocol development, informatics infrastructure, and the coordination of network-wide meetings and conferences. Mechanism of Support. This FOA utilizes the NIH Cooperative Agreement (U01) award mechanism. Parallel FOAs for other EDRN components include RFA-CA-09-017 (U01) for BDLs, RFA-CA-09-019 (U24) for BRLs, and RFA-CA-09-020 (U24) for DMCC.