Validation and Field Testing of Novel Biomarkers of Response to Environmental Stressors (R01)

The summary for the Validation and Field Testing of Novel Biomarkers of Response to Environmental Stressors (R01) Federal Grant is detailed below. It contains information such as the Catalog of Federal Domestic Assistance (CFDA) number, who is eligible for the grant, how much grant money will be awarded, important deadlines, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed in the Grant Announcement Contact section. If these sections are incomplete, please visit the website of the government agency that is offering this grant.


	Federal Grant Title:	Validation and Field Testing of Novel Biomarkers of Response to Environmental Stressors (R01)
	CFDA Number:	93.113
	CFDA Description:	Environmental Health
	Federal Agency Name:	National Institutes of Health
	Category of Funding Activity:	Education Environment Health
	Category Explanation:	Information not provided
	Opportunity Category:	Discretionary
	Funding Opportunity Number:	RFA-ES-10-008
	Document Type:	Grants Notice
	Funding Instrument Type:	Grant
	Posted Date:	Aug 13, 2010
	Creation Date:	Aug 13, 2010
	Original Closing Date for Applications:	Oct 21, 2010
	Current Closing Date for Applications:	Oct 21, 2010
	Archive Date:	Nov 21, 2010
	Expected Number of Awards:	Information not provided
	Estimated Total Program Funding:	$2,555,000
	Federal Grant Award Ceiling:	$300,000
	Federal Grant Award Floor:	Information not provided
	Cost Sharing or Matching Requirement:	No

Applicants Eligible for this Grant: State governments - County governments - City or township governments - Special district governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Public housing authorities/Indian housing authorities - Native American tribal organizations (other than Federally recognized tribal governments) - Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Grant Description: Purpose. This FOA solicits grant applications from institutions/organizations to conduct pilot testing of novel candidate biomarkers and technologies that measure biological responses to chemical toxicants and other environmental stressors. Through collaborations with existing human population studies, investigators will conduct a rigorous evaluation of the performance of novel biomarkers and technologies under a range of exposure levels and collection and storage conditions, to establish the potential and feasibility of applying these novel approaches to large-scale epidemiology and gene-environment studies. Applicants will be expected to describe characteristics of their candidate biomarkers or technologies (e.g., laboratory validation studies, limits of detection, and preliminary data from discovery cohort studies) that demonstrate their suitability for further pilot testing. The goal of this 2-year program is to assess the performance (including testing for sensitivity, specificity, reliability and reproducibility) of these novel approaches in independent cohorts. The emphasis of this FOA is the validation of promising biomarkers and technologies; projects to discover and develop new technology and biomarkers of response are not appropriate to this solicitation and will be returned as nonresponsive. Mechanism of Support. This FOA will utilize the R01 award mechanism and runs in parallel with an FOA of similar scientific scope, RFA-ES-10-007, that encourages applications to pilot test and validate new tools for measuring exposure to chemical and lifestyle stressors. Funds Available and Anticipated Number of Awards. NIEHS, NIAAA, and NIDA intend to commit a combined total of $2,555,000 to fund 5 to 6 awards through this FOA.
Link to Full Grant Announcement: http://grants.nih.gov/grants/guide/rfa-files/rfa-es-10-008.html
Grant Announcement Contact: NIH OER WebmasterFBOWebmaster@OD.NIH.GOV
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