Viral and Host Genetic Factors Regulating HIV-Associated CNS Disease (R01)

The summary for the Viral and Host Genetic Factors Regulating HIV-Associated CNS Disease (R01) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Viral and Host Genetic Factors Regulating HIV-Associated CNS Disease (R01): Purpose. The National Institute of Mental Health (NIMH) and The National Institute of Neurological Disorders and Stroke (NINDS) solicit research grant applications to support studies focused on viral and host genetic factors involved in HIV-1 Associated Neurocognitive Disorders (HAND) in the setting of highly active anti-retroviral therapy (HAART). Recent clinical studies indicate that over 50% of HIV-infected patients manifest HAND despite receiving HAART. The focus of this initiative is to encourage studies to discover novel genetic paradigms that may account for the interactions between the virus, the host, and the therapeutic drugs in the central nervous system (CNS) that result in the pathogenesis, progression, and clinical manifestations of HAND. The use of state-of-the-art genetic approaches (including transcriptomics, phenomics, epigenomics, whole genome association studies, next generation sequencing, exome sequencing, and systems biology) to identify and validate (including in vitro models, animal models, and human samples) viral and host genetic factors which influence the pathophysiology of HAND are encouraged. Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism and runs in parallel with an FOA of identical scientific scope, MH-11-021, which encourages applications under the Exploratory/Developmental Grant (R21) award mechanism. Funds Available and Anticipated Number of Awards. NIMH has set aside a total of $2.0 million in FY 2011 and NINDS a total of $1.0 million for this FOA and the companion announcement. It is anticipated that 5-7 R01 awards will be funded.

Federal Grant Title:	Viral and Host Genetic Factors Regulating HIV-Associated CNS Disease (R01)
Federal Agency Name:	National Institutes of Health
Grant Categories:	Health
Type of Opportunity:	Discretionary
Funding Opportunity Number:	RFA-MH-11-020
Type of Funding:	Grant
CFDA Numbers:	93.242
CFDA Descriptions:	Mental Health Research Grants
Current Application Deadline:	Jan 06, 2011
Original Application Deadline:	Jan 06, 2011
Posted Date:	Jul 29, 2010
Creation Date:	Jul 29, 2010
Archive Date:	Feb 06, 2011
Total Program Funding:	$3,000,000
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching:	No

Applicants Eligible for this Grant: State governments - County governments - City or township governments - Special district governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Public housing authorities/Indian housing authorities - Native American tribal organizations (other than Federally recognized tribal governments) - Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Link to Full Grant Announcement: Information not provided
Grant Announcement Contact: NIH OER [email protected]
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