Genomic Research in AAT-Deficiency and Sarcoidosis study (GRADS) Cooperative Research Project Grant: Genomics and Informatics Center (GIC) (U01)

The summary for the Genomic Research in AAT-Deficiency and Sarcoidosis study (GRADS) Cooperative Research Project Grant: Genomics and Informatics Center (GIC) (U01) Federal Grant is detailed below. It contains information such as the Catalog of Federal Domestic Assistance (CFDA) number, who is eligible for the grant, how much grant money will be awarded, important deadlines, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed in the Grant Announcement Contact section. If these sections are incomplete, please visit the website of the government agency that is offering this grant.


	Federal Grant Title:	Genomic Research in AAT-Deficiency and Sarcoidosis study (GRADS) Cooperative Research Project Grant: Genomics and Informatics Center (GIC) (U01)
	CFDA Number:	93.838
	CFDA Description:	Lung Diseases Research
	Federal Agency Name:	National Institutes of Health
	Category of Funding Activity:	Health
	Category Explanation:	Information not provided
	Opportunity Category:	Discretionary
	Funding Opportunity Number:	RFA-HL-12-014
	Document Type:	Grants Notice
	Funding Instrument Type:	Cooperative Agreement
	Posted Date:	Feb 02, 2011
	Creation Date:	Feb 02, 2011
	Original Closing Date for Applications:	May 17, 2011
	Current Closing Date for Applications:	May 17, 2011
	Archive Date:	Jun 17, 2011
	Expected Number of Awards:	Information not provided
	Estimated Total Program Funding:	$12,000,000
	Federal Grant Award Ceiling:	Information not provided
	Federal Grant Award Floor:	Information not provided
	Cost Sharing or Matching Requirement:	No

Applicants Eligible for this Grant: State governments - County governments - City or township governments - Special district governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Public housing authorities/Indian housing authorities - Native American tribal organizations (other than Federally recognized tribal governments) - Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Grant Description: The purpose of this funding opportunity announcement (FOA), issued by NHLBI, NIH, is to invite applications to participate in the NHLBI Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis (GRADS) program, which will assemble a multidisciplinary team of investigators to conduct state-of-art genomic, microbiomics and phenotypic studies of two serious and understudied conditions that affect the lungs: Alpha-1 Antitrypsin Deficiency (AAT) and sarcoidosis. GRADS will include multiple Clinical Centers and one Genomics and Informatics Center (GIC). This FOA solicits applications for the GIC and runs in parallel with a separate FOA that solicits applications for the Clinical Centers (see RFA-HL-12-013). The four main functions of the GRADS GIC are: (1) coordinate activities for the Clinical Centers that will recruit, clinically and immuno- phenotype AAT and sarcoidosis subjects and obtain biospecimens from them, (2) perform transcriptome and microbiome analyses (mRNA, miRNA, viro-, phylo-chip) of the samples obtained by the Clinical Centers, (3) analyze -omic data, testing for associations with the clinical and immune- phenotypes, and (4) prepare a dataset for deposit in the NHLBI BioLINCC repository (https://biolincc.nhlbi.nih.gov/new_data_set_policy/) for distribution to external investigators. This program will require multidisciplinary research collaboration among genomic and microbiome scientists, bioinformaticians, and clinicians with expertise in these diseases.
Link to Full Grant Announcement: http://grants.nih.gov/grants/guide/rfa-files/rfa-hl-12-014.html
Grant Announcement Contact: NIH OER WebmasterFBOWebmaster@OD.NIH.GOV
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster [FBOWebmaster@OD.NIH.GOV]
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