Optimizing Recovery and Preservation of Endogenous Insulin Secretion in Individuals with Prediabetes or Recent Onset of Type 2 Diabetes (U01)

The summary for the Optimizing Recovery and Preservation of Endogenous Insulin Secretion in Individuals with Prediabetes or Recent Onset of Type 2 Diabetes (U01) Federal Grant is detailed below. It contains information such as the Catalog of Federal Domestic Assistance (CFDA) number, who is eligible for the grant, how much grant money will be awarded, important deadlines, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed in the Grant Announcement Contact section. If these sections are incomplete, please visit the website of the government agency that is offering this grant.


	Federal Grant Title:	Optimizing Recovery and Preservation of Endogenous Insulin Secretion in Individuals with Prediabetes or Recent Onset of Type 2 Diabetes (U01)
	CFDA Number:	93.847
	CFDA Description:	Diabetes, Digestive, and Kidney Diseases Extramural Research
	Federal Agency Name:	National Institutes of Health
	Category of Funding Activity:	Food and Nutrition Health
	Category Explanation:	Information not provided
	Opportunity Category:	Discretionary
	Funding Opportunity Number:	RFA-DK-10-013
	Document Type:	Grants Notice
	Funding Instrument Type:	Cooperative Agreement
	Posted Date:	Nov 24, 2010
	Creation Date:	Nov 24, 2010
	Original Closing Date for Applications:	Mar 24, 2011
	Current Closing Date for Applications:	Mar 24, 2011
	Archive Date:	Apr 24, 2011
	Expected Number of Awards:	Information not provided
	Estimated Total Program Funding:	$4,000,000
	Federal Grant Award Ceiling:	Information not provided
	Federal Grant Award Floor:	Information not provided
	Cost Sharing or Matching Requirement:	No

Applicants Eligible for this Grant: State governments - County governments - City or township governments - Special district governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Public housing authorities/Indian housing authorities - Native American tribal organizations (other than Federally recognized tribal governments) - Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Grant Description: This FOA, issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), solicits applications for clinical studies to investigate strategies that promote the recovery and maintenance of endogenous insulin secretion among individuals who have prediabetes or are early in the course of type 2 diabetes. Specifically, the aim of this initiative is 1) To assess whether short, intensive interventions can substantially improve the pattern and magnitude of the endogenous insulin response, the extent to which recovery is possible and to identify the factors associated with recovery and retention of endogenous insulin secretion, and 2) To determine the duration of the effect and whether this will facilitate achieving better glucose control. In addition, studies may seek to identify biomarkers that will simplify assessment of beta cell function and improve prediction of whether a given individual will respond positively to the intervention. Although each investigator will propose and conduct a unique protocol, collaboration will be required among awardees to establish common definitions, measures and procedures to promote comparisons of data across protocols.
Link to Full Grant Announcement: http://grants.nih.gov/grants/guide/rfa-files/rfa-dk-10-013.html
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