Synthetic Hemo-technologIEs to Locate and Disinfect (SHIELD)

The summary for the Synthetic Hemo-technologIEs to Locate and Disinfect (SHIELD) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the DARPA Biological Technologies Office, which is the U.S. government agency offering this grant.

Synthetic Hemo-technologIEs to Locate and Disinfect (SHIELD): The Synthetic Hemo-technologIEs to Locate and Disinfect (SHIELD) program will develop safe and effective prophylactic countermeasures to defeat bloodborne pathogens and prevent bloodstream infections (BSI) associated with combat wounds. The program will develop prophylactic countermeasures effective against both bacteria and fungi, pathogens that are responsible for the vast majority of BSI. State-of-the-art countermeasures to manage BSI include antifungals and antibiotics which can be toxic, ineffective, and be administered in an untimely manner. SHIELD will develop safe and effective broad-spectrum prophylaxes that will protect recipients from bloodborne bacteria and fungi and prevent BSI for up to 144 h.