Broad-Spectrum Antagonists For Editors (B-SAFE)

The summary for the Broad-Spectrum Antagonists For Editors (B-SAFE) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the DARPA Biological Technologies Office, which is the U.S. government agency offering this grant.
Broad-Spectrum Antagonists For Editors (B-SAFE): The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to identify and optimize novel molecules that exhibit inhibitory effects on Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR associated proteins (CRISPR-Cas) gene editing processes. The Broad-Spectrum Antagonists for Editors (B-SAFE) program is explicitly seeking transformative approaches enabling the discovery or design of novel inhibitors of gene editing technologies with enhanced activity, utility, and breadth of coverage. Novel inhibitor activity will be assessed in vitro over the course of the program and a subset of top performing molecules will be selected for scale-up at quantities sufficient for testing and evaluation by Department of Defense (DoD) stakeholders. In concert, DARPA is interested in exploring methods to rapidly discover inhibitor molecules for novel gene editing technologies beyond CRISPR-Cas systems to keep pace with the rapidly advancing field and promote the safe, controlled use of these technologies. Research that generates incremental improvements to the existing state-of-the-art are specifically excluded.
Federal Grant Title: Broad-Spectrum Antagonists For Editors (B-SAFE)
Federal Agency Name: DARPA Biological Technologies Office (DOD-DARPA-BTO)
Grant Categories: Science and Technology and other Research and Development
Type of Opportunity: Discretionary
Funding Opportunity Number: HR001124S0032
Type of Funding: Cooperative Agreement
CFDA Numbers: 12.910
CFDA Descriptions: Information not provided
Current Application Deadline: August 12th, 2024
Original Application Deadline: August 12th, 2024
Posted Date: June 14th, 2024
Creation Date: June 14th, 2024
Archive Date: September 11th, 2024
Total Program Funding:
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching: No
Last Updated: June 14th, 2024
Applicants Eligible for this Grant
Others (see text field entitled "Additional Information on Eligibility" for clarification.)
Additional Information on Eligibility
All responsible sources capable of satisfying the Government's needs may submit a proposal that shall be considered by DARPA. See the Eligibility Information section of the BAA for more information.
Link to Full Grant Announcement
SAM.gov Contract Opportunities
Grant Announcement Contact
BAA Coordinator
[email protected]
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