Centers for Innovation in Membrane Protein Production

The summary for the Centers for Innovation in Membrane Protein Production grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Centers for Innovation in Membrane Protein Production: This Request for Applications (RFA) solicits proposals to establish Centers for Innovation in Membrane Protein Production. The goals of these Centers will be to create enabling technologies and to focus on innovative, high-impact, and multidisciplinary approaches to sample preparation of structurally and functionally intact membrane proteins for structure determination. The collaborative and coordinated effort made possible by multiple, interdisciplinary investigators associated with research Centers is required to accelerate technological advances in this important area. The goal of the Centers, not possible with other funding mechanisms or previous program announcements, will be the multidisciplinary and non-hypothesis-driven technology development of innovative tools and methods for the expression, solubilization, stabilization, reconstitution, and purification of membrane proteins. The Centers will disseminate their results, methods, and materials in a timely manner. They will also track state-of-the-art developments in membrane protein production and structure determination as guides in the selection of appropriate subprojects, cores, approaches, and targets. It is expected that the activities of the Centers for Innovation in Membrane Protein Production will complement the activities of investigator-initiated research, as supported by the R01, R21, and P01 mechanisms, and the goals of the NIGMS Protein Structure Initiative research centers. Because no single institution may have the variety of expertise required for membrane protein preparation and characterization, Centers involving multiple, cooperating institutions bringing together innovative combinations of scientific disciplines will be encouraged.